Kara G. Lassen, Ph.D.

Affiliations: 
2005 Johns Hopkins University, Baltimore, MD 
Area:
Immunology, Cell Biology
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"Kara Lassen"

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Robert F. Siliciano grad student 2005 Johns Hopkins
 (Transcriptional and post-transcriptional mechanisms maintain HIV -1 latency in resting CD4+ T cells in vivo.)
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Publications

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Tam JM, Reedy JL, Lukason DP, et al. (2019) Tetraspanin CD82 Organizes Dectin-1 into Signaling Domains to Mediate Cellular Responses to . Journal of Immunology (Baltimore, Md. : 1950)
Chan JK, Bhattacharyya D, Lassen KG, et al. (2013) Calcium/calcineurin synergizes with prostratin to promote NF-κB dependent activation of latent HIV. Plos One. 8: e77749
Lassen KG, Hebbeler AM, Bhattacharyya D, et al. (2012) A flexible model of HIV-1 latency permitting evaluation of many primary CD4 T-cell reservoirs. Plos One. 7: e30176
Sakane N, Kwon HS, Pagans S, et al. (2011) Activation of HIV transcription by the viral Tat protein requires a demethylation step mediated by lysine-specific demethylase 1 (LSD1/KDM1). Plos Pathogens. 7: e1002184
Lobritz MA, Lassen KG, Arts EJ. (2011) HIV-1 replicative fitness in elite controllers. Current Opinion in Hiv and Aids. 6: 214-20
Doitsh G, Cavrois M, Lassen K, et al. (2011) 113 Murder on the HIV Express: Insights into How CD4 T Cells Are Killed in Lymphoid Tissues Jaids Journal of Acquired Immune Deficiency Syndromes. 56: 45
Doitsh G, Cavrois M, Lassen KG, et al. (2010) Abortive HIV infection mediates CD4 T cell depletion and inflammation in human lymphoid tissue. Cell. 143: 789-801
Lassen KG, Wissing S, Lobritz MA, et al. (2010) Identification of two APOBEC3F splice variants displaying HIV-1 antiviral activity and contrasting sensitivity to Vif. The Journal of Biological Chemistry. 285: 29326-35
Johnston SH, Lobritz MA, Nguyen S, et al. (2009) A quantitative affinity-profiling system that reveals distinct CD4/CCR5 usage patterns among human immunodeficiency virus type 1 and simian immunodeficiency virus strains. Journal of Virology. 83: 11016-26
Lassen KG, Lobritz MA, Bailey JR, et al. (2009) Elite suppressor-derived HIV-1 envelope glycoproteins exhibit reduced entry efficiency and kinetics. Plos Pathogens. 5: e1000377
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