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Karen A. O'Connell, Ph.D.

Affiliations: 
2011 Johns Hopkins University, Baltimore, MD 
Area:
Virology Biology, Immunology
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"Karen O'Connell"
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Robert F. Siliciano grad student 2011 Johns Hopkins
 (HIV-1 infection in patients who control viremia without the use of antiretroviral therapy.)

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Buckheit RW, Allen TG, Alme A, et al. (2012) Host factors dictate control of viral replication in two HIV-1 controller/chronic progressor transmission pairs. Nature Communications. 3: 716
O'Connell KA, Skevington SM. (2012) An international quality of life instrument to assess wellbeing in adults who are HIV-positive: A short form of the WHOQOL-HIV (31 items) Aids and Behavior. 16: 452-460
Salgado M, Rabi SA, O'Connell KA, et al. (2011) Prolonged control of replication-competent dual- tropic human immunodeficiency virus-1 following cessation of highly active antiretroviral therapy. Retrovirology. 8: 97
O'Connell KA, Rabi SA, Siliciano RF, et al. (2011) CD4+ T cells from elite suppressors are more susceptible to HIV-1 but produce fewer virions than cells from chronic progressors. Proceedings of the National Academy of Sciences of the United States of America. 108: E689-98
O'Connell KA, Hegarty RW, Siliciano RF, et al. (2011) Viral suppression of multiple escape mutants by de novo CD8(+) T cell responses in a human immunodeficiency virus-1 infected elite suppressor. Retrovirology. 8: 63
Spivak AM, Salgado M, Rabi SA, et al. (2011) Circulating monocytes are not a major reservoir of HIV-1 in elite suppressors. Journal of Virology. 85: 10399-403
Gaillard S, Dinoso JB, Marsh JA, et al. (2011) Sustained elite suppression of replication competent HIV-1 in a patient treated with rituximab based chemotherapy. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. 51: 195-8
Rabi SA, O'Connell KA, Nikolaeva D, et al. (2011) Unstimulated primary CD4+ T cells from HIV-1-positive elite suppressors are fully susceptible to HIV-1 entry and productive infection. Journal of Virology. 85: 979-86
Salgado M, Brennan TP, O'Connell KA, et al. (2010) Evolution of the HIV-1 nef gene in HLA-B*57 positive elite suppressors. Retrovirology. 7: 94
O'Connell KA, Pelz RK, Dinoso JB, et al. (2010) Prolonged control of an HIV type 1 escape variant following treatment interruption in an HLA-B*27-positive patient. Aids Research and Human Retroviruses. 26: 1307-11
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