Craig A. Leach, Ph.D.
Affiliations: | 2003 | University of Virginia, Charlottesville, VA |
Area:
Microbiology Biology, Molecular BiologyGoogle:
"Craig Leach"Parents
Sign in to add mentor| D L. Brautigan | grad student | 2003 | UVA | |
| (Cellular regulation of type 1 protein phosphatase inhibitor 2.) | ||||
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Publications
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| Altun M, Kramer HB, Willems LI, et al. (2011) Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes. Chemistry & Biology. 18: 1401-12 |
| O'Leary B, Fedosejevs ET, Hill AT, et al. (2011) Tissue-specific expression and post-translational modifications of plant- and bacterial-type phosphoenolpyruvate carboxylase isozymes of the castor oil plant, Ricinus communis L. Journal of Experimental Botany. 62: 5485-95 |
| Tian X, Isamiddinova NS, Peroutka RJ, et al. (2011) Characterization of selective ubiquitin and ubiquitin-like protease inhibitors using a fluorescence-based multiplex assay format. Assay and Drug Development Technologies. 9: 165-73 |
| Uhrig RG, She YM, Leach CA, et al. (2008) Regulatory monoubiquitination of phosphoenolpyruvate carboxylase in germinating castor oil seeds. The Journal of Biological Chemistry. 283: 29650-7 |
| Nicholson B, Leach CA, Goldenberg SJ, et al. (2008) Characterization of ubiquitin and ubiquitin-like-protein isopeptidase activities. Protein Science : a Publication of the Protein Society. 17: 1035-43 |
| Satinover DL, Leach CA, Stukenberg PT, et al. (2004) Activation of Aurora-A kinase by protein phosphatase inhibitor-2, a bifunctional signaling protein. Proceedings of the National Academy of Sciences of the United States of America. 101: 8625-30 |
| Eto M, Leach C, Tountas NA, et al. (2003) Phosphoprotein inhibitors of protein phosphatase-1. Methods in Enzymology. 366: 243-60 |
| Leach C, Shenolikar S, Brautigan DL. (2003) Phosphorylation of phosphatase inhibitor-2 at centrosomes during mitosis. The Journal of Biological Chemistry. 278: 26015-20 |
| Leach C, Eto M, Brautigan DL. (2002) Domains of type 1 protein phosphatase inhibitor-2 required for nuclear and cytoplasmic localization in response to cell-cell contact. Journal of Cell Science. 115: 3739-45 |
| Blackie JA, Bloomer JC, Brown MJ, et al. (2002) The discovery of SB-435495. A potent, orally active inhibitor of lipoprotein-associated phospholipase A(2) for evaluation in man. Bioorganic & Medicinal Chemistry Letters. 12: 2603-6 |