Todd D. Prickett, Ph.D.

Affiliations: 
2007 University of Virginia, Charlottesville, VA 
Area:
Cell Biology, Molecular Biology
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"Todd Prickett"

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D L. Brautigan grad student 2007 UVA
 (alpha-4 and TAB4 in regulation of protein phosphatases and kinases.)
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Publications

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Prickett TD, Zerlanko B, Gartner JJ, et al. (2014) Somatic mutations in MAP3K5 attenuate its proapoptotic function in melanoma through increased binding to thioredoxin. The Journal of Investigative Dermatology. 134: 452-60
Prickett TD, Ninomiya-Tsuji J, Broglie P, et al. (2008) TAB4 stimulates TAK1-TAB1 phosphorylation and binds polyubiquitin to direct signaling to NF-kappaB. The Journal of Biological Chemistry. 283: 19245-54
Yang J, Roe SM, Prickett TD, et al. (2007) The structure of Tap42/alpha4 reveals a tetratricopeptide repeat-like fold and provides insights into PP2A regulation. Biochemistry. 46: 8807-15
Prickett TD, Brautigan DL. (2007) Cytokine activation of p38 mitogen-activated protein kinase and apoptosis is opposed by alpha-4 targeting of protein phosphatase 2A for site-specific dephosphorylation of MEK3. Molecular and Cellular Biology. 27: 4217-27
Prickett TD, Brautigan DL. (2006) The alpha4 regulatory subunit exerts opposing allosteric effects on protein phosphatases PP6 and PP2A. The Journal of Biological Chemistry. 281: 30503-11
Prickett TD, Brautigan DL. (2004) Overlapping binding sites in protein phosphatase 2A for association with regulatory A and alpha-4 (mTap42) subunits. The Journal of Biological Chemistry. 279: 38912-20
Terry-Lorenzo RT, Elliot E, Weiser DC, et al. (2002) Neurabins recruit protein phosphatase-1 and inhibitor-2 to the actin cytoskeleton. The Journal of Biological Chemistry. 277: 46535-43
Eto M, Elliott E, Prickett TD, et al. (2002) Inhibitor-2 regulates protein phosphatase-1 complexed with NimA-related kinase to induce centrosome separation. The Journal of Biological Chemistry. 277: 44013-20
Liu J, Prickett TD, Elliott E, et al. (2001) Phosphorylation and microtubule association of the Opitz syndrome protein mid-1 is regulated by protein phosphatase 2A via binding to the regulatory subunit alpha 4. Proceedings of the National Academy of Sciences of the United States of America. 98: 6650-5
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