Brian B. Gowen, Ph.D.

Affiliations: 
2000 University of South Carolina, Columbia, SC 
Area:
Cell Biology, Molecular Biology
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"Brian Gowen"

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Eugene Mayer grad student 2000 University of South Carolina
 (Selective adhesion of macrophages to denatured fibril -forming collagens is mediated by scavenger receptors.)
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Publications

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Chapman NS, Hulswit RJG, Westover JLB, et al. (2023) Multifunctional human monoclonal antibody combination mediates protection against Rift Valley fever virus at low doses. Nature Communications. 14: 5650
Westover JB, Naik S, Bailey KW, et al. (2022) Severe mammarenaviral disease in guinea pigs effectively treated by an orally bioavailable fusion inhibitor, alone or in combination with favipiravir. Antiviral Research. 208: 105444
Julander JG, Demarest JF, Taylor R, et al. (2021) An update on the progress of galidesivir (BCX4430), a broad-spectrum antiviral. Antiviral Research. 195: 105180
Gowen BB, Naik S, Westover JB, et al. (2021) Potent inhibition of arenavirus infection by a novel fusion inhibitor. Antiviral Research. 105125
Gowen BB, Hickerson BT, York J, et al. (2021) Second-generation live-attenuated Candid#1 vaccine virus resists reversion and protects against lethal Junín virus infection in guinea pigs. Journal of Virology
Chapman NS, Zhao H, Kose N, et al. (2021) Potent neutralization of Rift Valley fever virus by human monoclonal antibodies through fusion inhibition. Proceedings of the National Academy of Sciences of the United States of America. 118
Ranadheera C, Valcourt EJ, Warner BM, et al. (2020) Characterization of a novel STAT 2 knock-out hamster model of Crimean-Congo hemorrhagic fever virus pathogenesis. Scientific Reports. 10: 12378
Hawman DW, Haddock E, Meade-White K, et al. (2020) Efficacy of favipiravir (T-705) against Crimean-Congo hemorrhagic fever virus infection in cynomolgus macaques. Antiviral Research. 104858
Hickerson BT, Sefing EJ, Bailey KW, et al. (2020) Type I interferon underlies severe disease associated with Junín virus infection in mice. Elife. 9
Hickerson BT, Sefing EJ, Bailey KW, et al. (2020) Author response: Type I interferon underlies severe disease associated with Junín virus infection in mice Elife
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