Keith E. Giles, Ph.D.
Affiliations: | 2005 | Johns Hopkins University, Baltimore, MD |
Area:
Molecular Biology, Microbiology BiologyGoogle:
"Keith Giles"Parents
Sign in to add mentor| Karen Beemon | grad student | 2005 | Johns Hopkins | |
| (Rous sarcoma virus RNA: Splicing suppression and pseudogene formation.) | ||||
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Publications
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| Li Y, Li J, Wang J, et al. (2022) Premature transcription termination at the expanded GAA repeats and aberrant alternative polyadenylation contributes to the Frataxin transcriptional deficit in Friedreich's ataxia. Human Molecular Genetics |
| Zhou Z, Giles KE, Felsenfeld G. (2019) DNA·RNA triple helix formation can function as a -acting regulatory mechanism at the human locus. Proceedings of the National Academy of Sciences of the United States of America |
| Clarke AM, Engel KL, Giles KE, et al. (2018) NETSeq reveals heterogeneous nucleotide incorporation by RNA polymerase I. Proceedings of the National Academy of Sciences of the United States of America |
| Yang Z, Shah K, Busby T, et al. (2018) Hijacking a key chromatin modulator creates epigenetic vulnerability for Myc-driven cancer. The Journal of Clinical Investigation |
| Zhang Z, Jones AE, Wu W, et al. (2017) Role of remodeling and spacing factor 1 in histone H2A ubiquitination-mediated gene silencing. Proceedings of the National Academy of Sciences of the United States of America |
| Woolnough JL, Atwood BL, Liu Z, et al. (2016) The Regulation of rRNA Gene Transcription during Directed Differentiation of Human Embryonic Stem Cells. Plos One. 11: e0157276 |
| Atwood BL, Woolnough JL, Lefevre GM, et al. (2016) Human Argonaute 2 is tethered to ribosomal RNA through microRNA interactions. The Journal of Biological Chemistry |
| Woolnough JL, Atwood BL, Giles KE. (2015) Argonaute 2 Binds Directly to tRNA Genes and Promotes Gene Repression in cis. Molecular and Cellular Biology. 35: 2278-94 |
| Yang W, Lee YH, Jones AE, et al. (2014) The histone H2A deubiquitinase Usp16 regulates embryonic stem cell gene expression and lineage commitment. Nature Communications. 5: 3818 |
| Zhang Z, Jones A, Joo HY, et al. (2013) USP49 deubiquitinates histone H2B and regulates cotranscriptional pre-mRNA splicing. Genes & Development. 27: 1581-95 |