Rachel L. Edwards, Ph.D.
Affiliations: | 2008 | University of Michigan, Ann Arbor, Ann Arbor, MI |
Area:
Microbiology Biology, Molecular BiologyGoogle:
"Rachel Edwards"Parents
Sign in to add mentorMichele S. Swanson | grad student | 2008 | University of Michigan | |
(Metabolic cues and regulatory proteins that govern Legionella pneumophila differentiation and virulence.) |
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Publications
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Edwards RL, Heueck I, Lee SG, et al. (2020) Potent, specific MEPicides for treatment of zoonotic staphylococci. Plos Pathogens. 16: e1007806 |
Gnädig NF, Stokes BH, Edwards RL, et al. (2020) Insights into the intracellular localization, protein associations and artemisinin resistance properties of Plasmodium falciparum K13. Plos Pathogens. 16: e1008482 |
Edwards RL, Brothers RC, Wang X, et al. (2017) MEPicides: potent antimalarial prodrugs targeting isoprenoid biosynthesis. Scientific Reports. 7: 8400 |
San Jose G, Jackson ER, Haymond A, et al. (2016) Structure-Activity Relationships of the MEPicides: N-Acyl and O-linked Analogs of FR900098 as Inhibitors of Dxr from Mycobacterium tuberculosis and Yersinia pestis. Acs Infectious Diseases |
Imlay LS, Armstrong CM, Masters MC, et al. (2015) Plasmodium IspD (2-C-Methyl-D-erythritol 4-Phosphate Cytidyltransferase), an Essential and Druggable Antimalarial Target. Acs Infectious Diseases. 1: 157-167 |
Guggisberg AM, Park J, Edwards RL, et al. (2014) A sugar phosphatase regulates the methylerythritol phosphate (MEP) pathway in malaria parasites. Nature Communications. 5: 4467 |
Edwards RL, Bryan A, Jules M, et al. (2013) Nicotinic acid modulates Legionella pneumophila gene expression and induces virulence traits. Infection and Immunity. 81: 945-55 |
Edwards RL, Jules M, Sahr T, et al. (2010) The Legionella pneumophila LetA/LetS two-component system exhibits rheostat-like behavior. Infection and Immunity. 78: 2571-83 |
Edwards RL, Dalebroux ZD, Swanson MS. (2009) Legionella pneumophila couples fatty acid flux to microbial differentiation and virulence. Molecular Microbiology. 71: 1190-1204 |
Dalebroux ZD, Edwards RL, Swanson MS. (2009) SpoT governs Legionella pneumophila differentiation in host macrophages. Molecular Microbiology. 71: 640-58 |