James A. Coker, Ph.D.

Affiliations: 
2004 Pennsylvania State University, State College, PA, United States 
Area:
Biochemistry, Microbiology Biology
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"James Coker"

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Jean E. Brenchley grad student 2004 Penn State
 (Structure and function relationships in the cold -active beta-galactosidase, BgaS, examining theories of enzyme cold -adaptation.)
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Publications

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Coker JA. (2016) Extremophiles and biotechnology: current uses and prospects. F1000research. 5
Moran-Reyna A, Coker JA. (2014) The effects of extremes of pH on the growth and transcriptomic profiles of three haloarchaea. F1000research. 3: 168
Capes MD, Coker JA, Gessler R, et al. (2011) The information transfer system of halophilic archaea. Plasmid. 65: 77-101
Coker JA, DasSarma P, Capes M, et al. (2009) Multiple replication origins of Halobacterium sp. strain NRC-1: properties of the conserved orc7-dependent oriC1. Journal of Bacteriology. 191: 5253-61
Lu Q, Han J, Zhou L, et al. (2008) Dissection of the regulatory mechanism of a heat-shock responsive promoter in Haloarchaea: a new paradigm for general transcription factor directed archaeal gene regulation. Nucleic Acids Research. 36: 3031-42
Coker JA, DasSarma P, Kumar J, et al. (2007) Transcriptional profiling of the model Archaeon Halobacterium sp. NRC-1: responses to changes in salinity and temperature. Saline Systems. 3: 6
Coker JA, Brenchley JE. (2006) Protein engineering of a cold-active beta-galactosidase from Arthrobacter sp. SB to increase lactose hydrolysis reveals new sites affecting low temperature activity. Extremophiles : Life Under Extreme Conditions. 10: 515-24
DasSarma S, Berquist BR, Coker JA, et al. (2006) Post-genomics of the model haloarchaeon Halobacterium sp. NRC-1. Saline Systems. 2: 3
Coker JA, Sheridan PP, Loveland-Curtze J, et al. (2003) Biochemical characterization of a beta-galactosidase with a low temperature optimum obtained from an Antarctic arthrobacter isolate. Journal of Bacteriology. 185: 5473-82
Al-Khaldi SF, Coker J, Shen JR, et al. (2000) Characterization of site-directed mutants in manganese-stabilizing protein (MSP) of Synechocystis sp. PCC6803 unable to grow photoautotrophically in the absence of cytochrome c-550 Plant Molecular Biology. 43: 33-41
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