Scott B. Lovitch, Ph.D.

Affiliations: 
2007 Washington University, Saint Louis, St. Louis, MO 
Area:
Immunology
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"Scott Lovitch"

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Emil Unanue grad student 2007 Washington University
 (Conformational isomers of a peptide-class II MHC complex: Mechanism of formation and biological significance.)
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Publications

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Griffin GK, Weirather JL, Roemer M, et al. (2020) Spatial Signatures Identify Immune Escape via PD-1 as a Defining Feature of T-cell/Histiocyte-rich Large B-cell Lymphoma. Blood
Clement RL, Daccache J, Mohammed MT, et al. (2019) Follicular regulatory T cells control humoral and allergic immunity by restraining early B cell responses. Nature Immunology
Rodig SJ, Gusenleitner D, Jackson DG, et al. (2018) MHC proteins confer differential sensitivity to CTLA-4 and PD-1 blockade in untreated metastatic melanoma. Science Translational Medicine. 10
Rodig S, Gusenleitner D, Jackson D, et al. (2017) Association of distinct baseline tissue biomarkers with response to nivolumab (NIVO) and ipilimumab (IPI) in melanoma: CheckMate 064. Journal of Clinical Oncology. 35: 9515-9515
Ron-Harel N, Santos D, Ghergurovich JM, et al. (2016) Mitochondrial Biogenesis and Proteome Remodeling Promote One-Carbon Metabolism for T Cell Activation. Cell Metabolism. 24: 104-17
Saha A, O'Connor RS, Thangavelu G, et al. (2016) Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality. The Journal of Clinical Investigation
Paterson AM, Lovitch SB, Sage PT, et al. (2015) Deletion of CTLA-4 on regulatory T cells during adulthood leads to resistance to autoimmunity. The Journal of Experimental Medicine. 212: 1603-21
Saha A, O'Connor RS, Thangavelu G, et al. (2015) Loss of Programmed Death Ligand-1 Expression on Donor T Cells Lessens Acute Graft-Versus-Host Disease Lethality Blood. 126: 147-147
Sage PT, Paterson AM, Lovitch SB, et al. (2014) The coinhibitory receptor CTLA-4 controls B cell responses by modulating T follicular helper, T follicular regulatory, and T regulatory cells. Immunity. 41: 1026-39
Lovitch SB, Esparza TJ, Schweitzer G, et al. (2007) Activation of type B T cells after protein immunization reveals novel pathways of in vivo presentation of peptides. Journal of Immunology (Baltimore, Md. : 1950). 178: 122-33
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