Jorge E. Galan

Affiliations: 
Yale University, New Haven, CT 
Area:
Microbiology Biology
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"Jorge Galan"

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Robert O. Watson grad student Yale
Maria D. Lara-Tejero grad student 2001 Yale
Alessandra R. Pancetti grad student 2004 Yale
Erik A. Haghjoo grad student 2006 Yale
Veronica Novik grad student 2008 Yale
Julie E. Button grad student 2011 Yale
Heather A. Carleton-Romer grad student 2012 Yale
Stefania Spanò post-doc Yale School of Medicine
Emily Z. Guo post-doc 2017- Yale (Neurotree)
Florian Schueder post-doc 2021- Yale (Physics Tree)
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Publications

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Guo E, Chou SZ, Lara-Tejero M, et al. (2023) Cryo-EM structure of the bacterial effector protein SipA bound to F-actin reveals a unique mechanism for filament stabilization. Biorxiv : the Preprint Server For Biology
Lian H, Park D, Chen M, et al. (2023) Parkinson's disease kinase LRRK2 coordinates a cell-intrinsic itaconate-dependent defence pathway against intracellular Salmonella. Nature Microbiology
Soto JE, Galán JE, Lara-Tejero M. (2022) Assembly and architecture of the type III secretion sorting platform. Proceedings of the National Academy of Sciences of the United States of America. 119: e2218010119
Chang SJ, Hsu YT, Chen Y, et al. (2022) Typhoid toxin sorting and exocytic transport from Typhi infected cells. Elife. 11
Guo EZ, Galán JE. (2021) Cryo-EM structure of the needle filament tip complex of the type III secretion injectisome. Proceedings of the National Academy of Sciences of the United States of America. 118
Galán JE. (2021) Salmonella Typhimurium and inflammation: a pathogen-centric affair. Nature Reviews. Microbiology
Lian H, Jiang K, Tong M, et al. (2021) The Salmonella effector protein SopD targets Rab8 to positively and negatively modulate the inflammatory response. Nature Microbiology
Chen M, Sun H, Boot M, et al. (2020) Itaconate is an effector of a Rab GTPase cell-autonomous host defense pathway against . Science (New York, N.Y.). 369: 450-455
Geiger T, Lara-Tejero M, Xiong Y, et al. (2020) Mechanisms of substrate recognition by a typhoid toxin secretion-associated muramidase. Elife. 9
Geiger T, Lara-Tejero M, Xiong Y, et al. (2020) Author response: Mechanisms of substrate recognition by a typhoid toxin secretion-associated muramidase Elife
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