Alexander Mankin

Affiliations: 
University of Illinois at Chicago, Health Sciences Center, Chicago, IL 60612, United States 
Area:
Microbiology Biology
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"Alexander Mankin"
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Publications

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Koller TO, Berger MJ, Morici M, et al. (2024) Paenilamicins from the honey bee pathogen are context-specific translocation inhibitors of protein synthesis. Biorxiv : the Preprint Server For Biology
Mangano K, Marks J, Klepacki D, et al. (2022) Context-based sensing of orthosomycin antibiotics by the translating ribosome. Nature Chemical Biology. 18: 1277-1286
Meydan S, Klepacki D, Karthikeyan S, et al. (2022) Response to: Lack of evidence for ribosomal frameshifting in ATP7B mRNA decoding. Molecular Cell
Tsai K, Stojković V, Lee DJ, et al. (2022) Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics. Nature Structural & Molecular Biology. 29: 162-171
Zhang Y, Aleksashin NA, Klepacki D, et al. (2022) The context of the ribosome binding site in mRNAs defines specificity of action of kasugamycin, an inhibitor of translation initiation. Proceedings of the National Academy of Sciences of the United States of America. 119
Mitcheltree MJ, Pisipati A, Syroegin EA, et al. (2021) A synthetic antibiotic class overcoming bacterial multidrug resistance. Nature
Beckert B, Leroy EC, Sothiselvam S, et al. (2021) Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics. Nature Communications. 12: 4466
Svetlov MS, Koller TO, Meydan S, et al. (2021) Context-specific action of macrolide antibiotics on the eukaryotic ribosome. Nature Communications. 12: 2803
Svetlov MS, Syroegin EA, Aleksandrova EV, et al. (2021) Structure of Erm-modified 70S ribosome reveals the mechanism of macrolide resistance. Nature Chemical Biology
Svetlov MS, Cohen S, Alsuhebany N, et al. (2020) A long-distance rRNA base pair impacts the ability of macrolide antibiotics to kill bacteria. Proceedings of the National Academy of Sciences of the United States of America
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