Christian Melander

Affiliations: 
North Carolina State University, Raleigh, NC 
Area:
Organic Chemistry, Microbiology Biology
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"Christian Melander"

Parents

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Peter B. Dervan grad student Caltech (Chemistry Tree)
David A. Horne grad student Columbia (Chemistry Tree)
Joel M. Gottesfeld grad student 2002-2004 The Scripps Research Institute, La Jolla, CA (Chemistry Tree)

Children

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Thomas E. Ballard grad student 2008 NCSU
Virginia A. Burns grad student 2009 NCSU
Robert W. Huigens grad student 2009 NCSU
Justin J. Richards grad student 2009 NCSU
Christine L. Heinecke grad student 2010 NCSU
Rachel A. Kudgus grad student 2010 NCSU
Cynthia A. Bunders grad student 2012 NCSU
Zhaoming Su grad student 2012 NCSU
Erick A. Lindsey grad student 2013 NCSU
Tyler L. Harris grad student 2014 NCSU
Marine J. Minvielle grad student 2014 NCSU
Meghan S. Blackledge post-doc 2012-2014 (Chemistry Tree)
BETA: Related publications

Publications

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Nemeth AM, Melander RJ, Smith RD, et al. (2024) Identification of a 2-aminobenzimidazole scaffold that potentiates gram-positive selective antibiotics against gram-negative bacteria. Chembiochem : a European Journal of Chemical Biology. e202400127
Bennett AN, Woolard KJ, Sorge A, et al. (2023) Spectrum of activity of anti-biofilm compounds: Evaluation of activity against biofilm-forming ESKAPE pathogens. Biofilm. 6: 100158
Liu C, Zhang H, Peng X, et al. (2023) Small Molecule Attenuates Bacterial Virulence by Targeting Conserved Response Regulator. Mbio. e0013723
Marrujo SA, Hubble VB, Yang J, et al. (2023) Dimeric 2-aminoimidazoles are highly active adjuvants for gram-positive selective antibiotics against Acinetobacter baumannii. European Journal of Medicinal Chemistry. 253: 115329
Onyedibe KI, Nemeth AM, Dayal N, et al. (2023) Re-sensitization of Multidrug-Resistant and Colistin-Resistant Gram-Negative Bacteria to Colistin by Povarov/Doebner-Derived Compounds. Acs Infectious Diseases
Siwawannapong K, Nemeth AM, Melander RJ, et al. (2022) Simple Dipyrrin Analogues of Prodigiosin for use as Colistin Adjuvants. Chemmedchem
Belardinelli JM, Li W, Martin KH, et al. (2022) 2-Aminoimidazoles Inhibit Biofilms in a Zinc-Dependent Manner. International Journal of Molecular Sciences. 23
Woolard KJ, Sandala JL, Melander RJ, et al. (2022) Development of small molecules that work cooperatively with ciprofloxacin to clear salmonella biofilms in a chronic gallbladder carriage model. European Journal of Medicinal Chemistry. 232: 114203
Melander CC, Zeiler MJ, Connors GM, et al. (2022) Synthesis, Stereochemical Confirmation, and Derivatization of a Clerodane Diterpene That Sensitizes Methicillin-Resistant Staphylococcus aureus to β-Lactam Antibiotics. Angewandte Chemie (International Ed. in English)
Li H, Mattingly AE, Jania LA, et al. (2021) Benzimidazole Isosteres of Salicylanilides Are Highly Active Colistin Adjuvants. Acs Infectious Diseases. 7: 3303-3313
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