Tiffany R. Keepers, Ph.D.

Affiliations: 
2007 University of Virginia, Charlottesville, VA 
Area:
Microbiology Biology
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"Tiffany Keepers"

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Tom Obrig grad student 2007 UVA
 (Renal inflammation in a shiga toxin plus lipopolysaccharide induced murine model of hemolytic uremic syndrome.)
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Obata F, Tohyama K, Bonev AD, et al. (2008) Shiga toxin 2 affects the central nervous system through receptor globotriaosylceramide localized to neurons. The Journal of Infectious Diseases. 198: 1398-406
Roche JK, Keepers TR, Gross LK, et al. (2007) CXCL1/KC and CXCL2/MIP-2 are critical effectors and potential targets for therapy of Escherichia coli O157:H7-associated renal inflammation. The American Journal of Pathology. 170: 526-37
Keepers TR, Gross LK, Obrig TG. (2007) Monocyte chemoattractant protein 1, macrophage inflammatory protein 1 alpha, and RANTES recruit macrophages to the kidney in a mouse model of hemolytic-uremic syndrome. Infection and Immunity. 75: 1229-36
Keepers TR, Psotka MA, Gross LK, et al. (2006) A murine model of HUS: Shiga toxin with lipopolysaccharide mimics the renal damage and physiologic response of human disease. Journal of the American Society of Nephrology : Jasn. 17: 3404-14
Guessous F, Marcinkiewicz M, Polanowska-Grabowska R, et al. (2005) Shiga toxin 2 and lipopolysaccharide cause monocytic THP-1 cells to release factors which activate platelet function. Thrombosis and Haemostasis. 94: 1019-27
Houpt ER, Glembocki DJ, Obrig TG, et al. (2002) The mouse model of amebic colitis reveals mouse strain susceptibility to infection and exacerbation of disease by CD4+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 169: 4496-503
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