Claudia X. Dominguez, Ph.D.

Affiliations: 
2014 Yale University, New Haven, CT 
Area:
Immunology
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"Claudia Dominguez"

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Susan M. Kaech grad student 2014 Yale
 (ZEB2 promotes the terminal differentiation of CD8 effector T cells.)
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Publications

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Kapoor VN, Müller S, Keerthivasan S, et al. (2021) Gremlin 1 fibroblastic niche maintains dendritic cell homeostasis in lymphoid tissues. Nature Immunology
Buechler MB, Kim KW, Onufer EJ, et al. (2019) A Stromal Niche Defined by Expression of the Transcription Factor WT1 Mediates Programming and Homeostasis of Cavity-Resident Macrophages. Immunity
Guan T, Dominguez CX, Amezquita RA, et al. (2018) ZEB1, ZEB2, and the miR-200 family form a counterregulatory network to regulate CD8T cell fates. The Journal of Experimental Medicine
Pikor NB, Astarita JL, Summers-Deluca L, et al. (2015) Integration of Th17- and Lymphotoxin-Derived Signals Initiates Meningeal-Resident Stromal Cell Remodeling to Propagate Neuroinflammation. Immunity. 43: 1160-73
Dominguez CX, Amezquita RA, Guan T, et al. (2015) The transcription factors ZEB2 and T-bet cooperate to program cytotoxic T cell terminal differentiation in response to LCMV viral infection. The Journal of Experimental Medicine
Chen JH, Perry CJ, Tsui YC, et al. (2015) Prostaglandin E2 and programmed cell death 1 signaling coordinately impair CTL function and survival during chronic viral infection. Nature Medicine. 21: 327-34
Backer RA, Helbig C, Gentek R, et al. (2014) A central role for Notch in effector CD8(+) T cell differentiation. Nature Immunology. 15: 1143-51
Dominguez C, Cui W. (2013) Inside out: decoding the transcriptome of effector and memory T cells Immunology and Cell Biology. 91: 389-390
Joshi NS, Cui W, Dominguez CX, et al. (2011) Increased numbers of preexisting memory CD8 T cells and decreased T-bet expression can restrain terminal differentiation of secondary effector and memory CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 187: 4068-76
Monk KR, Naylor SG, Glenn TD, et al. (2009) A G protein-coupled receptor is essential for Schwann cells to initiate myelination. Science (New York, N.Y.). 325: 1402-5
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