Manoj Thapa, Ph.D.

Affiliations: 
2008 University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States 
Area:
Immunology, Microbiology Biology
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"Manoj Thapa"

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Daniel J. J. Carr grad student 2008 University of Oklahoma Health Sciences Center
 (Chemokines and chemokine receptors that mediate immune defense to genital herpes simplex virus type 2 (HSV-2) infection.)
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Publications

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Gridley J, Holland B, Salinas E, et al. (2024) Concerted synergy between viral-specific IgG and CD8+ T cells is critical for clearance of an HCV-related rodent hepacivirus. Hepatology (Baltimore, Md.)
Thapa M, Tedesco D, Gumber S, et al. (2020) Blockade of BAFF Reshapes the Hepatic B Cell Receptor Repertoire and Attenuates Autoantibody Production in Cholestatic Liver Disease. Journal of Immunology (Baltimore, Md. : 1950)
Tedesco D, Thapa M, Chin CY, et al. (2018) Alterations in Intestinal Microbiota Lead to Production of Interleukin 17 by Intrahepatic γδ T-cell Receptor-positive Cells and Pathogenesis of Cholestatic Liver Disease. Gastroenterology
Mimche PN, Lee CM, Mimche SM, et al. (2018) EphB2 receptor tyrosine kinase promotes hepatic fibrogenesis in mice via activation of hepatic stellate cells. Scientific Reports. 8: 2532
Tedesco D, Thapa M, Gumber S, et al. (2016) CD4+ Foxp3+ T cells promote aberrant IgG production and maintain CD8+ T cell suppression during chronic liver disease. Hepatology (Baltimore, Md.)
Mimche PN, Brady LM, Bray CF, et al. (2015) The receptor tyrosine kinase EphB2 promotes hepatic fibrosis in mice. Hepatology (Baltimore, Md.)
Thapa M, Chinnadurai R, Velazquez VM, et al. (2015) Liver fibrosis occurs through dysregulation of MyD88-dependent innate B-cell activity. Hepatology (Baltimore, Md.). 61: 2067-79
Velazquez VM, Uebelhoer LS, Thapa M, et al. (2015) Systems biological analyses reveal the hepatitis C virus (HCV)-specific regulation of hematopoietic development. Hepatology (Baltimore, Md.). 61: 843-56
Dunham RM, Thapa M, Velazquez VM, et al. (2013) Hepatic stellate cells preferentially induce Foxp3+ regulatory T cells by production of retinoic acid. Journal of Immunology (Baltimore, Md. : 1950). 190: 2009-16
Wuest TR, Thapa M, Zheng M, et al. (2011) CXCL10 expressing hematopoietic-derived cells are requisite in defense against HSV-1 infection in the nervous system of CXCL10 deficient mice Journal of Neuroimmunology. 234: 103-108
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