Mark D. Mannie
Affiliations: | Microbiology and Immunology | East Carolina University, Greenville, NC, United States |
Area:
Immunology, Molecular BiologyGoogle:
"Mark Mannie"Children
Sign in to add trainee| Dhaval M. Patel | grad student | 2001 | East Carolina University |
| Mindi R. Walker | grad student | 2002 | East Carolina University |
| Jennifer L. Blanchfield | grad student | 2010 | East Carolina University |
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Publications
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| Nickle RA, DeOca KB, Garcia BL, et al. (2023) Soluble CD25 imposes a low-zone IL-2 signaling environment that favors competitive outgrowth of antigen-experienced CD25 regulatory and memory T cells. Cellular Immunology. 384: 104664 |
| Islam SMT, Won J, Khan M, et al. (2021) Hypoxia-inducible factor-1 drives divergent immunomodulatory functions in the pathogenesis of autoimmune diseases. Immunology |
| DeOca KB, Moorman CD, Garcia BL, et al. (2020) Low-Zone IL-2 Signaling: Fusion Proteins Containing Linked CD25 and IL-2 Domains Sustain Tolerogenic Vaccination and Promote Dominance of FOXP3 Tregs . Frontiers in Immunology. 11: 541619 |
| Mannie MD, DeOca KB, Bastian AG, et al. (2020) Tolerogenic vaccines: Targeting the antigenic and cytokine niches of FOXP3 regulatory T cells. Cellular Immunology. 355: 104173 |
| Moorman CD, Bastian AG, DeOca KB, et al. (2020) A GM-CSF-neuroantigen tolerogenic vaccine elicits inefficient antigen recognition events below the CD40L triggering threshold to expand CD4 CD25 FOXP3 Tregs that inhibit experimental autoimmune encephalomyelitis (EAE). Journal of Neuroinflammation. 17: 180 |
| Moorman CD, Curtis AD, Bastian AG, et al. (2018) A GMCSF-Neuroantigen Tolerogenic Vaccine Elicits Systemic Lymphocytosis of CD4 CD25 FOXP3 Regulatory T Cells in Myelin-Specific TCR Transgenic Mice Contingent Upon Low-Efficiency T Cell Antigen Receptor Recognition. Frontiers in Immunology. 9: 3119 |
| Wilkinson DS, Ghosh D, Nickle RA, et al. (2017) Partial CD25 Antagonism Enables Dominance of Antigen-Inducible CD25high FOXP3+ Regulatory T Cells As a Basis for a Regulatory T Cell-Based Adoptive Immunotherapy. Frontiers in Immunology. 8: 1782 |
| Wang D, Ghosh D, Islam SM, et al. (2016) IFN-β Facilitates Neuroantigen-Dependent Induction of CD25+ FOXP3+ Regulatory T Cells That Suppress Experimental Autoimmune Encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950) |
| Ghosh D, Curtis AD, Wilkinson DS, et al. (2016) Depletion of CD4+ CD25+ regulatory T cells confers susceptibility to experimental autoimmune encephalomyelitis (EAE) in GM-CSF-deficient Csf2-/- mice. Journal of Leukocyte Biology |
| Patial S, Curtis AD, Lai WS, et al. (2016) Enhanced stability of tristetraprolin mRNA protects mice against immune-mediated inflammatory pathologies. Proceedings of the National Academy of Sciences of the United States of America. 113: 1865-70 |