Kristopher A. Lofgren, Ph.D.

Affiliations: 
2005-2010 Microbiology, Immunology, and Cancer Biology University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Cell Biology, Oncology
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"Kristopher Lofgren"

Parents

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Carol A. Lange grad student 2010 UMN
 (Modeling Brk/PTK6 Expression in the Mammary Epithelium.)
Donald E. Ingber post-doc 2010-2013 Boston Children's Hospital/Harvard Medical School (Neurotree)
Paraic A. Kenny post-doc 2013-2015 Albert Einstein College of Medicine of Yeshiva University
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Publications

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Lofgren KA, Kenny PA. (2023) Grb7 knockout mice develop normally but litters born to knockout females fail to thrive. Developmental Dynamics : An Official Publication of the American Association of Anatomists
Lofgren KA, Reker NC, Sreekumar S, et al. (2022) Pan-cancer distribution of cleaved cell-surface amphiregulin, the target of the GMF-1A3 antibody drug conjugate. Antibody Therapeutics. 5: 226-231
Parsons BM, Meier DR, Gurda GT, et al. (2022) Exceptional Response to Crizotinib in an MET-Amplified Triple-Negative Breast Tumor. Jco Precision Oncology. 1: 1-6
Lofgren KA, Sreekumar S, Jenkins EC, et al. (2021) Anti-tumor efficacy of an MMAE-conjugated antibody targeting cell surface TACE/ADAM17-cleaved Amphiregulin in breast cancer. Antibody Therapeutics. 4: 252-261
Parsons BM, Meier DR, Richmond CS, et al. (2020) Acquisition of Cabozantinib-Sensitive MET D1228N Mutation During Progression on Crizotinib in MET-Amplified Triple-Negative Breast Cancer. Clinical Breast Cancer
Meier DR, Girtman MA, Lofgren KA, et al. (2019) Amphiregulin deletion strongly attenuates the development of estrogen receptor-positive tumors in p53 mutant mice. Breast Cancer Research and Treatment
Lofgren K, Emmanuel N, Meier D, et al. (2019) SAT-331 Elucidating the Role of Breast Cancer Specific GATA3 Mutation in Estrogen Receptor Positive Breast Cancer Journal of the Endocrine Society. 3
Parsons BM, Meier DR, Sreekumar S, et al. (2019) Abstract 1317: Exceptional responses to crizotinib in breast cancer patients with somatic MET and ROS1 alterations Cancer Research. 79: 1317-1317
Emmanuel N, Lofgren KA, Peterson EA, et al. (2018) Mutant GATA3 Actively Promotes the Growth of Normal and Malignant Mammary Cells. Anticancer Research. 38: 4435-4441
Meier DR, Lofgren KA, Gurda GT, et al. (2018) Adaptation of an amplicon-based human cancer next-generation sequencing panel assay for murine tumors. Analytical Biochemistry
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