Sarjubhai A. Patel, Ph.D.

Affiliations: 
2000 University of Montana, Missoula, MT 
Area:
Neuroscience Biology, Pharmacology
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"Sarjubhai Patel"

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Richard Bridges grad student 2000 Univ. Montana
 (Characterisation of high-affinity, chloride -dependent L-glutamate transport in glial tumour cells.)
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Publications

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Hitt DM, Zwicker JD, Chao CK, et al. (2021) Inhibition of the Vesicular Glutamate Transporter (VGLUT) with Congo Red Analogs: New Binding Insights. Neurochemical Research
Nehser M, Dark J, Schweitzer D, et al. (2019) System X Antiporter Inhibitors: Azo-Linked Amino-Naphthyl-Sulfonate Analogues of Sulfasalazine. Neurochemical Research
Carrigan CN, Patel SA, Cox HD, et al. (2014) The development of benzo- and naphtho-fused quinoline-2,4-dicarboxylic acids as vesicular glutamate transporter (VGLUT) inhibitors reveals a possible role for neuroactive steroids. Bioorganic & Medicinal Chemistry Letters. 24: 850-4
Newell JL, Keyari CM, McDaniel SW, et al. (2014) Novel di-aryl-substituted isoxazoles act as noncompetitive inhibitors of the system Xc(-) cystine/glutamate exchanger. Neurochemistry International. 73: 132-8
Matti AA, Mirzaei J, Rudolph J, et al. (2013) Microwave accelerated synthesis of isoxazole hydrazide inhibitors of the system xc- transporter: Initial homology model. Bioorganic & Medicinal Chemistry Letters. 23: 5931-5
Bridges RJ, Natale NR, Patel SA. (2012) System xc⁻ cystine/glutamate antiporter: an update on molecular pharmacology and roles within the CNS. British Journal of Pharmacology. 165: 20-34
Pathmajeyan MS, Patel SA, Carroll JA, et al. (2011) Increased excitatory amino acid transport into murine prion protein knockout astrocytes cultured in vitro. Glia. 59: 1684-94
Ahmed SK, Etoga JL, Patel SA, et al. (2011) Use of the hydantoin isostere to produce inhibitors showing selectivity toward the vesicular glutamate transporter versus the obligate exchange transporter system x(c)(-). Bioorganic & Medicinal Chemistry Letters. 21: 4358-62
Seib TM, Patel SA, Bridges RJ. (2011) Regulation of the system x(C)- cystine/glutamate exchanger by intracellular glutathione levels in rat astrocyte primary cultures. Glia. 59: 1387-401
Etoga JL, Ahmed SK, Patel S, et al. (2010) Conformationally-restricted amino acid analogues bearing a distal sulfonic acid show selective inhibition of system x(c)(-) over the vesicular glutamate transporter. Bioorganic & Medicinal Chemistry Letters. 20: 2680-3
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