Alex S. Petrucelli, Ph.D.
Affiliations: | 2011 | Immunobiology | University of Arizona, Tucson, AZ |
Area:
Virology Biology, Immunology, Microbiology BiologyGoogle:
"Alex Petrucelli"Parents
Sign in to add mentor| Felicia D. Goodrum | grad student | 2011 | University of Arizona | |
| (The role of pUL138 in HCMV persistence.) | ||||
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Publications
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| Deng M, Tam JW, Wang L, et al. (2020) TRAF3IP3 negatively regulates cytosolic RNA induced anti-viral signaling by promoting TBK1 K48 ubiquitination. Nature Communications. 11: 2193 |
| Li X, Deng M, Petrucelli AS, et al. (2019) Viral DNA Binding to NLRC3, an Inhibitory Nucleic Acid Sensor, Unleashes STING, a Cyclic Dinucleotide Receptor that Activates Type I Interferon. Immunity. 50: 591-599.e6 |
| Uchimura T, Oyama Y, Deng M, et al. (2018) The Innate Immune Sensor NLRC3 Acts as a Rheostat that Fine-Tunes T Cell Responses in Infection and Autoimmunity. Immunity. 49: 1049-1061.e6 |
| Swanson KV, Junkins RD, Kurkjian CJ, et al. (2017) A noncanonical function of cGAMP in inflammasome priming and activation. The Journal of Experimental Medicine |
| Ma Z, Hopcraft SE, Yang F, et al. (2017) NLRX1 negatively modulates type I IFN to facilitate KSHV reactivation from latency. Plos Pathogens. 13: e1006350 |
| Buehler J, Zeltzer S, Reitsma J, et al. (2016) Opposing Regulation of the EGF Receptor: A Molecular Switch Controlling Cytomegalovirus Latency and Replication. Plos Pathogens. 12: e1005655 |
| Guo H, König R, Deng M, et al. (2016) NLRX1 Sequesters STING to Negatively Regulate the Interferon Response, Thereby Facilitating the Replication of HIV-1 and DNA Viruses. Cell Host & Microbe. 19: 515-528 |
| Zhang L, Mo J, Swanson KV, et al. (2014) NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING. Immunity. 40: 329-41 |
| Petrucelli A, Umashankar M, Zagallo P, et al. (2012) Interactions between proteins encoded within the human cytomegalovirus UL133-UL138 locus. Journal of Virology. 86: 8653-62 |
| Umashankar M, Petrucelli A, Cicchini L, et al. (2011) A novel human cytomegalovirus locus modulates cell type-specific outcomes of infection. Plos Pathogens. 7: e1002444 |