Rongze Lu, Ph.D.

Affiliations: 
2011 Graduate School of Biological Sciences City of Hope's Irell & Manella Graduate School of Biomedical Sciences 
Area:
Immunology
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"Rongze Lu"

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John E. Shively grad student 2011 City of Hope's Irell & Manella Graduate School of Biomedical Sciences
 (CEACAM1 is a negative regulator of myeloid-cell-mediated tumor angiogenesis and Syk mediated inflammasome activation in eutrophils.)
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Publications

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Bedognetti D, Ceccarelli M, Galluzzi L, et al. (2019) Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop. Journal For Immunotherapy of Cancer. 7: 131
Danaher P, Warren S, Lu R, et al. (2018) Pan-cancer adaptive immune resistance as defined by the Tumor Inflammation Signature (TIS): results from The Cancer Genome Atlas (TCGA). Journal For Immunotherapy of Cancer. 6: 63
Turan T, Kannan D, Patel M, et al. (2018) Immune oncology, immune responsiveness and the theory of everything. Journal For Immunotherapy of Cancer. 6: 50
Ho WS, Wang H, Maggio D, et al. (2018) Pharmacologic inhibition of protein phosphatase-2A achieves durable immune-mediated antitumor activity when combined with PD-1 blockade. Nature Communications. 9: 2126
Ho WSC, Sizdahkhani S, Hao S, et al. (2017) LB-100, a novel Protein Phosphatase 2A (PP2A) inhibitor, sensitizes malignant meningioma cells to the therapeutic effects of radiation. Cancer Letters
Ho WS, Wang H, Kovach JS, et al. (2017) Abstract LB-193: Protein phosphatase 2A inhibition,with a novel small molecule inhibitor, LB-100, achieves durable immune-mediated antitumor activity when combined with PD1 blockade in a preclinical model Cancer Research. 77
Rutz S, Kayagaki N, Phung QT, et al. (2015) Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells. Nature. 518: 417-21
Xin H, Lu R, Lee H, et al. (2013) G-protein-coupled receptor agonist BV8/prokineticin-2 and STAT3 protein form a feed-forward loop in both normal and malignant myeloid cells. The Journal of Biological Chemistry. 288: 13842-9
Lu R, Pan H, Shively JE. (2012) CEACAM1 negatively regulates IL-1β production in LPS activated neutrophils by recruiting SHP-1 to a SYK-TLR4-CEACAM1 complex. Plos Pathogens. 8: e1002597
Lu R, Kujawski M, Pan H, et al. (2012) Tumor angiogenesis mediated by myeloid cells is negatively regulated by CEACAM1. Cancer Research. 72: 2239-50
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