Adel A. Malek, Ph.D.

Affiliations: 
2012 Molecular Pathogenesis Dartmouth College, Hanover, NH, United States 
Area:
Microbiology Biology
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"Adel Malek"

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Deborah A. Hogan grad student 2012 Dartmouth
 (Characterization of transporters involved in uptake of choline and other trimethylamine-containing compounds in the opportunistic pathogen Pseudomonas aeruginosa.)
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Publications

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Vilchèze C, Copeland J, Keiser TL, et al. (2018) Rational Design of Biosafety Level 2-Approved, Multidrug-Resistant Strains of Mycobacterium tuberculosis through Nutrient Auxotrophy. Mbio. 9
Vergnolle O, Xu H, Tufariello JM, et al. (2016) Post-Translational Acetylation of MbtA Modulates Mycobacterial Siderophore Biosynthesis. The Journal of Biological Chemistry
Tufariello JM, Malek AA, Vilchèze C, et al. (2014) Enhanced specialized transduction using recombineering in Mycobacterium tuberculosis. Mbio. 5: e01179-14
Malek AA, Wargo MJ, Hogan DA. (2012) Absence of membrane phosphatidylcholine does not affect virulence and stress tolerance phenotypes in the opportunistic pathogen Pseudomonas aeruginosa. Plos One. 7: e30829
Malek AA, Chen C, Wargo MJ, et al. (2011) Roles of three transporters, CbcXWV, BetT1, and BetT3, in Pseudomonas aeruginosa choline uptake for catabolism. Journal of Bacteriology. 193: 3033-41
Chen C, Malek AA, Wargo MJ, et al. (2010) The ATP-binding cassette transporter Cbc (choline/betaine/carnitine) recruits multiple substrate-binding proteins with strong specificity for distinct quaternary ammonium compounds. Molecular Microbiology. 75: 29-45
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