Xazmin H. Lowman, Ph.D.
Affiliations: | 2012 | Microbiology, Immunology and Cancer Biology | University of Minnesota, Twin Cities, Minneapolis, MN |
Area:
Cell Biology, Molecular Biology, OncologyGoogle:
"Xazmin Lowman"Parents
Sign in to add mentor| Ameeta Kelekar | grad student | 2012 | UMN | |
| (A novel role for the pro-apoptotic protein Noxa in survival and glucose metabolism.) | ||||
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Publications
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| Ruiz BI, Lowman XH, Yang Y, et al. (2023) Alpha-Ketoglutarate Regulates Tnfrsf12a/Fn14 Expression via Histone Modification and Prevents Cancer-Induced Cachexia. Genes. 14 |
| Lowman XH, Hanse EA, Yang Y, et al. (2019) p53 Promotes Cancer Cell Adaptation to Glutamine Deprivation by Upregulating Slc7a3 to Increase Arginine Uptake. Cell Reports. 26: 3051-3060.e4 |
| Yang Y, Ishak Gabra MB, Hanse EA, et al. (2019) MiR-135 suppresses glycolysis and promotes pancreatic cancer cell adaptation to metabolic stress by targeting phosphofructokinase-1. Nature Communications. 10: 809 |
| Ishak Gabra MB, Yang Y, Lowman XH, et al. (2018) IKKβ activates p53 to promote cancer cell adaptation to glutamine deprivation. Oncogenesis. 7: 93 |
| Hanse EA, Ruan C, Kachman M, et al. (2017) Cytosolic malate dehydrogenase activity helps support glycolysis in actively proliferating cells and cancer. Oncogene |
| Tran TQ, Lowman XH, Reid MA, et al. (2016) Tumor-associated mutant p53 promotes cancer cell survival upon glutamine deprivation through p21 induction. Oncogene |
| Reid MA, Lowman XH, Pan M, et al. (2016) IKKβ promotes metabolic adaptation to glutamine deprivation via phosphorylation and inhibition of PFKFB3. Genes & Development |
| Yan Y, Hanse EA, Stedman K, et al. (2016) Transcription factor C/EBP-β induces tumor-suppressor phosphatase PHLPP2 through repression of the miR-17-92 cluster in differentiating AML cells. Cell Death and Differentiation |
| Das SG, Hermanson DL, Bleeker N, et al. (2013) Ethyl 2-amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017): a novel scaffold that resensitizes multidrug resistant leukemia cells to chemotherapy. Acs Chemical Biology. 8: 327-35 |
| Lowman XH, McDonnell MA, Kosloske A, et al. (2010) The proapoptotic function of Noxa in human leukemia cells is regulated by the kinase Cdk5 and by glucose. Molecular Cell. 40: 823-33 |