Hope B. O'Donnell, Ph.D.

Affiliations: 
2014 Microbiology, Immunology and Cancer Biology University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Immunology, Microbiology Biology, Cell Biology
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"Hope O'Donnell"

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Stephen J. McSorley grad student 2014 UMN
 (Eliciting Th1 effector functions: A mechanism and role for innate amplification of the Th1 response during infection.)
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Publications

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Omange RW, Kim SC, Kolhatkar NS, et al. (2025) AI discovery of TLR agonist-driven phenotypes reveals unique features of peripheral cells from healthy donors and ART-suppressed people living with HIV. Frontiers in Immunology. 16: 1541152
Snyder TM, Gittelman RM, Klinger M, et al. (2025) Magnitude and dynamics of the T-cell response to SARS-CoV-2 infection at both individual and population levels. Frontiers in Immunology. 15: 1488860
Snyder TM, Gittelman RM, Klinger M, et al. (2020) Magnitude and Dynamics of the T-Cell Response to SARS-CoV-2 Infection at Both Individual and Population Levels. Medrxiv : the Preprint Server For Health Sciences
Pham OH, O'Donnell H, Al-Shamkhani A, et al. (2017) T cell expression of IL-18R and DR3 is essential for non-cognate stimulation of Th1 cells and optimal clearance of intracellular bacteria. Plos Pathogens. 13: e1006566
O'Donnell H, Pham OH, Benoun JM, et al. (2015) Contaminated water delivery as a simple and effective method of experimental Salmonella infection. Future Microbiology. 10: 1615-27
O'Donnell H, McSorley SJ. (2014) Salmonella as a model for non-cognate Th1 cell stimulation. Frontiers in Immunology. 5: 621
O'Donnell H, Pham OH, Li LX, et al. (2014) Toll-like receptor and inflammasome signals converge to amplify the innate bactericidal capacity of T helper 1 cells. Immunity. 40: 213-24
Johanns TM, Law CY, Kalekar LA, et al. (2011) Early eradication of persistent Salmonella infection primes antibody-mediated protective immunity to recurrent infection. Microbes and Infection / Institut Pasteur. 13: 322-30
Jackson A, Nanton MR, O'Donnell H, et al. (2010) Innate immune activation during Salmonella infection initiates extramedullary erythropoiesis and splenomegaly. Journal of Immunology (Baltimore, Md. : 1950). 185: 6198-204
Lee SJ, O'Donnell H, McSorley SJ. (2010) B7-H1 (programmed cell death ligand 1) is required for the development of multifunctional Th1 cells and immunity to primary, but not secondary, Salmonella infection. Journal of Immunology (Baltimore, Md. : 1950). 185: 2442-9
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