Lai N. Chan, Ph.D.
Affiliations: | 2011 | University of California, Los Angeles, Los Angeles, CA |
Area:
Molecular Biology, Cell Biology, BiochemistryGoogle:
"Lai Chan"Parents
Sign in to add mentor| Fuyuhiko Tamanoi | grad student | 2011 | UCLA | |
| (Novel Chemical Biology Approaches to Studying Protein Geranylgeranylation.) | ||||
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Publications
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| Zimonjic DB, Chan LN, Tripathi V, et al. (2013) In vitro and in vivo effects of geranylgeranyltransferase I inhibitor P61A6 on non-small cell lung cancer cells. Bmc Cancer. 13: 198 |
| Chan LN, Fiji HD, Watanabe M, et al. (2011) Identification and characterization of mechanism of action of P61-E7, a novel phosphine catalysis-based inhibitor of geranylgeranyltransferase-I. Plos One. 6: e26135 |
| Chan LN, Watanabe M, Kwon O, et al. (2011) Small-Molecule Inhibitors of GGTase-I from the Heterocycle Library Derived from Phosphine Catalysis Enzymes. 30: 165-177 |
| Chan LN, Tamanoi F. (2011) Global Analysis of Prenylated Proteins by the Use of a Tagging via Substrate Approach Enzymes. 29: 195-206 |
| Chan LN, Hart C, Guo L, et al. (2009) A novel approach to tag and identify geranylgeranylated proteins. Electrophoresis. 30: 3598-606 |
| Lu J, Chan L, Fiji HD, et al. (2009) In vivo antitumor effect of a novel inhibitor of protein geranylgeranyltransferase-I. Molecular Cancer Therapeutics. 8: 1218-26 |
| Watanabe M, Fiji HD, Guo L, et al. (2008) Inhibitors of protein geranylgeranyltransferase I and Rab geranylgeranyltransferase identified from a library of allenoate-derived compounds. The Journal of Biological Chemistry. 283: 9571-9 |