Roberto Tinoco, Ph.D.
Affiliations: | 2010 | Biology | University of California, San Diego, La Jolla, CA |
Area:
Virology Biology, Microbiology BiologyGoogle:
"Roberto Tinoco"Parents
Sign in to add mentor| Elina I. Zuniga | grad student | 2010 | UCSD | |
| (Cell-intrinsic transforming growth factor-beta signaling mediates virus-specific CD8+ T cell deletion and lymphocytic choriomeningitis virus persistence in vivo.) | ||||
| Linda M Bradley | post-doc | Sanford Burnham Prebys Medical Discovery Institute (Neurotree) | ||
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Publications
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| Neubert EN, DeRogatis JM, Lewis SA, et al. (2023) HMGB2 regulates the differentiation and stemness of exhausted CD8 T cells during chronic viral infection and cancer. Nature Communications. 14: 5631 |
| Hope JL, Otero DC, Bae EA, et al. (2023) PSGL-1 attenuates early TCR signaling to suppress CD8 T cell progenitor differentiation and elicit terminal CD8 T cell exhaustion. Cell Reports. 42: 112436 |
| DeRogatis JM, Neubert EN, Viramontes KM, et al. (2023) Cell-Intrinsic CD38 Expression Sustains Exhausted CD8 T Cells by Regulating Their Survival and Metabolism during Chronic Viral Infection. Journal of Virology. e0022523 |
| Viramontes KM, Neubert EN, DeRogatis JM, et al. (2022) PD-1 Immune Checkpoint Blockade and PSGL-1 Inhibition Synergize to Reinvigorate Exhausted T Cells. Frontiers in Immunology. 13: 869768 |
| DeRogatis JM, Viramontes KM, Neubert EN, et al. (2022) Targeting the PSGL-1 Immune Checkpoint Promotes Immunity to PD-1 Resistant Melanoma. Cancer Immunology Research |
| Tinoco R, Neubert EN, Stairiker CJ, et al. (2021) PSGL-1 Is a T Cell Intrinsic Inhibitor That Regulates Effector and Memory Differentiation and Responses During Viral Infection. Frontiers in Immunology. 12: 677824 |
| DeRogatis JM, Viramontes KM, Neubert EN, et al. (2021) PSGL-1 Immune Checkpoint Inhibition for CD4 T Cell Cancer Immunotherapy. Frontiers in Immunology. 12: 636238 |
| Li Y, Elmén L, Segota I, et al. (2020) Prebiotic-Induced Anti-tumor Immunity Attenuates Tumor Growth. Cell Reports. 30: 1753-1766.e6 |
| Scortegagna M, Hockemeyer K, Dolgalev I, et al. (2020) Siah2 control of T-regulatory cells limits anti-tumor immunity. Nature Communications. 11: 99 |
| Li Y, Tinoco R, Elmén L, et al. (2019) Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5 mice. Nature Communications. 10: 1492 |