Nadejda Sigal, Ph.D.
Affiliations: | 2008 | BCH Biological Chemistry | Weizmann Institute of Science, Rehovot, Israel |
Area:
Pharmacy, BiochemistryGoogle:
"Nadejda Sigal"Parents
Sign in to add mentor| Eitan Bibi | grad student | 2008 | Weizmann Institute | |
| (Structural and functional aspects of secondary multidrug transport by MdfA.) | ||||
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Publications
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| Brenner M, Lobel L, Borovok I, et al. (2018) Controlled branched-chain amino acids auxotrophy in Listeria monocytogenes allows isoleucine to serve as a host signal and virulence effector. Plos Genetics. 14: e1007283 |
| Friedman S, Linsky M, Lobel L, et al. (2017) Metabolic genetic screens reveal multidimensional regulation of virulence gene expression in Listeria monocytogenes, and an aminopeptidase that is critical for PrfA protein activation. Infection and Immunity |
| Haber A, Friedman S, Lobel L, et al. (2017) L-glutamine Induces Expression of Listeria monocytogenes Virulence Genes. Plos Pathogens. 13: e1006161 |
| Sigal N, Kaplan Zeevi M, Weinstein S, et al. (2015) The human P-glycoprotein transporter enhances the type I interferon response to Listeria monocytogenes infection. Infection and Immunity. 83: 2358-68 |
| Lobel L, Sigal N, Borovok I, et al. (2015) The metabolic regulator CodY links Listeria monocytogenes metabolism to virulence by directly activating the virulence regulatory gene prfA. Molecular Microbiology. 95: 624-44 |
| Tadmor K, Pozniak Y, Burg Golani T, et al. (2014) Listeria monocytogenes MDR transporters are involved in LTA synthesis and triggering of innate immunity during infection. Frontiers in Cellular and Infection Microbiology. 4: 16 |
| Kaplan Zeevi M, Shafir NS, Shaham S, et al. (2013) Listeria monocytogenes multidrug resistance transporters and cyclic di-AMP, which contribute to type I interferon induction, play a role in cell wall stress. Journal of Bacteriology. 195: 5250-61 |
| Burg-Golani T, Pozniak Y, Rabinovich L, et al. (2013) Membrane chaperone SecDF plays a role in the secretion of Listeria monocytogenes major virulence factors Journal of Bacteriology. 195: 5262-5272 |
| Lobel L, Sigal N, Borovok I, et al. (2012) Integrative genomic analysis identifies isoleucine and CodY as regulators of Listeria monocytogenes virulence. Plos Genetics. 8: e1002887 |
| Rabinovich L, Sigal N, Borovok I, et al. (2012) Prophage excision activates Listeria competence genes that promote phagosomal escape and virulence. Cell. 150: 792-802 |