Greg Hussack, Ph.D.
Affiliations: | 2011 | Biochemistry, Microbiology and Immunology | University of Ottawa, Ottawa, ON, Canada |
Area:
Microbiology Biology, Immunology, ToxicologyGoogle:
"Greg Hussack"Parents
Sign in to add mentor| Jamshid Tanha | grad student | 2011 | University of Ottawa | |
| (Single-domain Antibody Inhibitors of Clostridium difficile Toxins.) | ||||
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Publications
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| Aguilar EN, Sagar S, Murray BR, et al. (2024) Structural Basis for Multivalent MUC16 Recognition and Robust Anti-Pancreatic Cancer Activity of Humanized Antibody AR9.6. Molecular Cancer Therapeutics |
| Kim DY, Kandalaft H, Lowden MJ, et al. (2023) Sequence tolerance of immunoglobulin variable domain framework regions to non-canonical intradomain disulfide linkages. The Journal of Biological Chemistry. 105278 |
| Lowden MJ, Lei EK, Hussack G, et al. (2023) Applications of High-Throughput DNA Sequencing to Single-Domain Antibody Discovery and Engineering. Methods in Molecular Biology (Clifton, N.J.). 2702: 489-540 |
| Rossotti MA, Trempe F, van Faassen H, et al. (2023) Isolation and Characterization of Single-Domain Antibodies from Immune Phage Display Libraries. Methods in Molecular Biology (Clifton, N.J.). 2702: 107-147 |
| Lei EK, Ryan S, van Faassen H, et al. (2023) Isolation and characterization of a VHH targeting the Acinetobacter baumannii cell surface protein CsuA/B. Applied Microbiology and Biotechnology. 1-14 |
| Hussack G, Rossotti MA, van Faassen H, et al. (2023) Corrigendum: Structure-guided design of a potent toxin A inhibitor. Frontiers in Microbiology. 14: 1167817 |
| Hussack G, Rossotti MA, van Faassen H, et al. (2023) Structure-guided design of a potent toxin A inhibitor. Frontiers in Microbiology. 14: 1110541 |
| Sheff J, Kelly J, Foss M, et al. (2022) Epitope mapping of a blood-brain barrier crossing antibody targeting the cysteine-rich region of IGF1R using hydrogen-exchange mass spectrometry enabled by electrochemical reduction. Journal of Biochemistry |
| Rossotti MA, van Faassen H, Tran AT, et al. (2022) Arsenal of nanobodies shows broad-spectrum neutralization against SARS-CoV-2 variants of concern in vitro and in vivo in hamster models. Communications Biology. 5: 933 |
| Yogi A, Hussack G, van Faassen H, et al. (2022) Brain Delivery of IGF1R5, a Single-Domain Antibody Targeting Insulin-like Growth Factor-1 Receptor. Pharmaceutics. 14 |