Kristen Pauken, Ph.D.

Affiliations: 
2013 Microbiology, Immunology and Cancer Biology University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Immunology
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"Kristen Pauken"

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Brian T. Fife grad student 2009-2013 UMN
 (The inhibitory receptor PD-1 differentially regulates effector and anergic autoreactive CD4 T cells during Type 1 Diabetes.)
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Publications

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Keshari S, Shavkunov AS, Miao Q, et al. (2023) Overlapping and Distinct Mechanisms of Effective Neoantigen Cancer Vaccines and Immune Checkpoint Therapy. Biorxiv : the Preprint Server For Biology
Rowe JH, Elia I, Shahid O, et al. (2023) Formate supplementation enhances anti-tumor CD8+ T cell fitness and efficacy of PD-1 blockade. Cancer Discovery
Collier JL, Pauken KE, Lee CAA, et al. (2023) Single-cell profiling reveals unique features of diabetogenic T cells in anti-PD-1-induced type 1 diabetes mice. The Journal of Experimental Medicine. 220
Schenkel JM, Pauken KE. (2023) Localization, tissue biology and T cell state - implications for cancer immunotherapy. Nature Reviews. Immunology
Alvarez-Breckenridge C, Markson SC, Stocking JH, et al. (2022) Microenvironmental landscape of human melanoma brain metastases in response to immune checkpoint inhibition. Cancer Immunology Research
Lagattuta KA, Kang JB, Nathan A, et al. (2022) Repertoire analyses reveal T cell antigen receptor sequence features that influence T cell fate. Nature Immunology
Pauken KE, Lagattuta KA, Lu BY, et al. (2022) TCR-sequencing in cancer and autoimmunity: barcodes and beyond. Trends in Immunology
Schenkel JM, Herbst RH, Canner D, et al. (2021) Conventional type I dendric cells maintain a reservoir of proliferative tumor-antigen specific TCF-1 CD8 T cells in tumor-draining lymph nodes. Immunity
Collier JL, Weiss SA, Pauken KE, et al. (2021) Not-so-opposite ends of the spectrum: CD8 T cell dysfunction across chronic infection, cancer and autoimmunity. Nature Immunology
Pauken KE, Torchia JA, Chaudhri A, et al. (2021) Emerging concepts in PD-1 checkpoint biology. Seminars in Immunology. 101480
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