Pallavi R. Sachdev, Ph.D.
Affiliations: | 2002 | Icahn School of Medicine at Mount Sinai, New York, NY, United States |
Area:
Molecular Biology, Cell BiologyGoogle:
"Pallavi Sachdev"Parents
Sign in to add mentor| Lu-Hai Wang | grad student | 2002 | Mount Sinai School of Medicine | |
| (Rho family GTPases and their upstream regulator, Vav3, in signaling and cell transformation mediated by receptor protein tyrosine kinases.) | ||||
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Publications
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| Janz JM, Ren Y, Looby R, et al. (2011) Direct interaction between an allosteric agonist pepducin and the chemokine receptor CXCR4. Journal of the American Chemical Society. 133: 15878-81 |
| Décaillot FM, Kazmi MA, Lin Y, et al. (2011) CXCR7/CXCR4 heterodimer constitutively recruits β-arrestin to enhance cell migration Journal of Biological Chemistry. 286: 32188-32197 |
| Grunbeck A, Huber T, Sachdev P, et al. (2011) Mapping the ligand-binding site on a G protein-coupled receptor (GPCR) using genetically encoded photocrosslinkers Biochemistry. 50: 3411-3413 |
| Tchernychev B, Ren Y, Sachdev P, et al. (2010) Discovery of a CXCR4 agonist pepducin that mobilizes bone marrow hematopoietic cells Proceedings of the National Academy of Sciences of the United States of America. 107: 22255-22259 |
| Ye S, Köhrer C, Huber T, et al. (2008) Site-specific incorporation of keto amino acids into functional G protein-coupled receptors using unnatural amino acid mutagenesis. The Journal of Biological Chemistry. 283: 1525-33 |
| Sachdev P, Zeng L, Wang LH. (2002) Distinct role of phosphatidylinositol 3-kinase and Rho family GTPases in Vav3-induced cell transformation, cell motility, and morphological changes. Journal of Biological Chemistry. 277: 17638-17648 |
| Zeng L, Sachdev P, Yan L, et al. (2000) Vav3 mediates receptor protein tyrosine kinase signaling, regulates GTPase activity, modulates cell morphology, and induces cell transformation. Molecular and Cellular Biology. 20: 9212-24 |