Yoko Kosaka, Ph.D.

Affiliations: 
2001 Dartmouth College, Hanover, NH, United States 
Area:
Immunology
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"Yoko Kosaka"

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Randolph J. Noelle grad student 2001 Dartmouth
 (Characterization of pathways and intermediates involved in CD40 signal transduction.)
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Publications

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Flynn PA, Long MD, Kosaka Y, et al. (2023) Leukemic mutation FLT3-ITD is retained in dendritic cells and disrupts their homeostasis leading to expanded Th17 frequency. Biorxiv : the Preprint Server For Biology
Romine KA, MacPherson K, Cho HJ, et al. (2023) BET inhibitors rescue anti-PD1 resistance by enhancing TCF7 accessibility in leukemia-derived terminally exhausted CD8 T cells. Leukemia
Moshofsky KB, Cho HJ, Wu G, et al. (2019) Acute myeloid leukemia-induced T-cell suppression can be reversed by inhibition of the MAPK pathway. Blood Advances. 3: 3038-3051
Leonard J, Kosaka Y, Newman MT, et al. (2018) Altered T Cell Subsets and Function in Patients with Acute Lymphoblastic Leukemia Blood. 132: 1547-1547
Leonard J, Kosaka Y, Malla P, et al. (2018) T-Cell Suppression By Src/ABL Kinase Inhibitors When Combined with Blinatumomab in Ph+ Acute Lymphoblastic Leukemia Blood. 132: 2694-2694
Lamble A, Kosaka Y, Huang F, et al. (2016) Mass Cytometry As a Modality to Identify Candidates for Immune Checkpoint Inhibitor Therapy within Acute Myeloid Leukemia Blood. 128: 2829-2829
Lamble A, Kosaka Y, Lo P, et al. (2015) Defining the Immune Microenvironment in Patients with Acute Myeloid Leukemia Blood. 126: 1374-1374
Siegers GM, Felizardo TC, Mathieson AM, et al. (2011) Anti-leukemia activity of in vitro-expanded human gamma delta T cells in a xenogeneic Ph+ leukemia model. Plos One. 6: e16700
Lind EF, Ahonen CL, Wasiuk A, et al. (2008) Dendritic cells require the NF-kappaB2 pathway for cross-presentation of soluble antigens. Journal of Immunology (Baltimore, Md. : 1950). 181: 354-63
Kosaka Y, Felices M, Berg LJ. (2006) Itk and Th2 responses: action but no reaction. Trends in Immunology. 27: 453-60
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