Marie-Luise Brennan, Ph.D.
Affiliations: | 2000 | University of California, Los Angeles, Los Angeles, CA |
Area:
Molecular Biology, PathologyGoogle:
"Marie-Luise Brennan"Parents
Sign in to add mentor| Aldons J. Lusis | grad student | 2000 | UCLA | |
| (An animal model to examine the role of myeloperoxidase in atherosclerosis and other inflammatory diseases.) | ||||
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| Bhattacharyya T, Nicholls SJ, Topol EJ, et al. (2008) Relationship of paraoxonase 1 (PON1) gene polymorphisms and functional activity with systemic oxidative stress and cardiovascular risk. Jama. 299: 1265-76 |
| Lee JC, Weissglas-Volkov D, Kyttälä M, et al. (2007) USF1 contributes to high serum lipid levels in Dutch FCHL families and U.S. whites with coronary artery disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 2222-7 |
| Eiserich JP, Baldus S, Brennan ML, et al. (2002) Myeloperoxidase, a leukocyte-derived vascular NO oxidase. Science (New York, N.Y.). 296: 2391-4 |
| Gukovskaya AS, Vaquero E, Zaninovic V, et al. (2002) Neutrophils and NADPH oxidase mediate intrapancreatic trypsin activation in murine experimental acute pancreatitis. Gastroenterology. 122: 974-84 |
| Brennan ML, Wu W, Fu X, et al. (2002) A tale of two controversies: defining both the role of peroxidases in nitrotyrosine formation in vivo using eosinophil peroxidase and myeloperoxidase-deficient mice, and the nature of peroxidase-generated reactive nitrogen species. The Journal of Biological Chemistry. 277: 17415-27 |
| Baldus S, Eiserich JP, Mani A, et al. (2001) Endothelial transcytosis of myeloperoxidase confers specificity to vascular ECM proteins as targets of tyrosine nitration. The Journal of Clinical Investigation. 108: 1759-70 |
| Gaut JP, Yeh GC, Tran HD, et al. (2001) Neutrophils employ the myeloperoxidase system to generate antimicrobial brominating and chlorinating oxidants during sepsis. Proceedings of the National Academy of Sciences of the United States of America. 98: 11961-6 |
| Brennan ML, Anderson MM, Shih DM, et al. (2001) Increased atherosclerosis in myeloperoxidase-deficient mice. The Journal of Clinical Investigation. 107: 419-30 |
| Brennan ML, Gaur A, Pahuja A, et al. (2001) Mice lacking myeloperoxidase are more susceptible to experimental autoimmune encephalomyelitis Journal of Neuroimmunology. 112: 97-105 |
| Vaquero E, Gukovskaya A, Brennan M, et al. (2000) Leukocyte NADPH oxidase but not myeloperoxidase regulates pancreatic trypsin activation in cerulein induced pancreatitis Gastroenterology. 118: A170 |