Charles T. Spencer, Ph.D.
Affiliations: | 2008 | Saint Louis University, St. Louis, MO, United States |
Area:
Immunology, Microbiology BiologyGoogle:
"Charles Spencer"Parents
Sign in to add mentor| Daniel F. Hoft | grad student | 2008 | Saint Louis University | |
| (Characterization of gammadelta T cells relevant for protective tuberculosis immunity: T cell specificity, antigen identification and mechanisms of inhibition.) | ||||
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Publications
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| Xia M, Hesser DC, De P, et al. (2016) A Subset of Protective γ9δ2 T cells is Activated by Novel Mycobacterial Lipid Components. Infection and Immunity |
| Spencer CT, Bezbradica JS, Ramos MG, et al. (2015) Viral infection causes a shift in the self peptide repertoire presented by human MHC class I molecules. Proteomics. Clinical Applications. 9: 1035-52 |
| Abate G, Spencer CT, Hamzabegovic F, et al. (2015) Mycobacteria-specific γ9δ2 T cells mediate both pathogen inhibitory and CD40L-dependent antigen presentation effects important for TB immunity. Infection and Immunity |
| Gilchuk P, Spencer CT, Conant SB, et al. (2013) Discovering naturally processed antigenic determinants that confer protective T cell immunity. The Journal of Clinical Investigation. 123: 1976-87 |
| Spencer CT, Dragovic SM, Conant SB, et al. (2013) Sculpting MHC class II-restricted self and non-self peptidome by the class I Ag-processing machinery and its impact on Th-cell responses. European Journal of Immunology. 43: 1162-72 |
| Spencer CT, Abate G, Sakala IG, et al. (2013) Granzyme A produced by γ(9)δ(2) T cells induces human macrophages to inhibit growth of an intracellular pathogen. Plos Pathogens. 9: e1003119 |
| Gordy LE, Bezbradica JS, Flyak AI, et al. (2011) IL-15 regulates homeostasis and terminal maturation of NKT cells. Journal of Immunology (Baltimore, Md. : 1950). 187: 6335-45 |
| Hoft DF, Babusis E, Worku S, et al. (2011) Live and inactivated influenza vaccines induce similar humoral responses, but only live vaccines induce diverse T-cell responses in young children Journal of Infectious Diseases. 204: 845-853 |
| Lee K, Gudapati P, Dragovic S, et al. (2010) Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways. Immunity. 32: 743-53 |
| Spencer CT, Gilchuk P, Dragovic SM, et al. (2010) Minor histocompatibility antigens: presentation principles, recognition logic and the potential for a healing hand. Current Opinion in Organ Transplantation. 15: 512-25 |