Shawn G. Payne, Ph.D.
Affiliations: | 2001 | University of Alberta, Edmonton, Alberta, Canada |
Area:
Cell Biology, Molecular BiologyGoogle:
"Shawn Payne"Parents
Sign in to add mentor| Larry Guilbert | grad student | 2001 | University of Alberta | |
| (The role of sphingolipids in the control of apoptosis in human placental primary trophoblasts.) | ||||
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Publications
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| Mitra P, Maceyka M, Payne SG, et al. (2007) Ceramide kinase regulates growth and survival of A549 human lung adenocarcinoma cells. Febs Letters. 581: 735-40 |
| Rosato RR, Maggio SC, Almenara JA, et al. (2006) The histone deacetylase inhibitor LAQ824 induces human leukemia cell death through a process involving XIAP down-regulation, oxidative injury, and the acid sphingomyelinase-dependent generation of ceramide. Molecular Pharmacology. 69: 216-25 |
| Johnstone ED, Mackova M, Das S, et al. (2005) Multiple anti-apoptotic pathways stimulated by EGF in cytotrophoblasts. Placenta. 26: 548-55 |
| Rahmani M, Reese E, Dai Y, et al. (2005) Coadministration of histone deacetylase inhibitors and perifosine synergistically induces apoptosis in human leukemia cells through Akt and ERK1/2 inactivation and the generation of ceramide and reactive oxygen species. Cancer Research. 65: 2422-32 |
| Maggio SC, Rosato RR, Kramer LB, et al. (2004) The histone deacetylase inhibitor MS-275 interacts synergistically with fludarabine to induce apoptosis in human leukemia cells. Cancer Research. 64: 2590-600 |
| Gupta S, Natarajan R, Payne SG, et al. (2004) Deoxycholic acid activates the c-Jun N-terminal kinase pathway via FAS receptor activation in primary hepatocytes. Role of acidic sphingomyelinase-mediated ceramide generation in FAS receptor activation. The Journal of Biological Chemistry. 279: 5821-8 |
| Liu H, Toman RE, Goparaju SK, et al. (2003) Sphingosine kinase type 2 is a putative BH3-only protein that induces apoptosis. The Journal of Biological Chemistry. 278: 40330-6 |
| Maceyka M, Payne SG, Milstien S, et al. (2002) Sphingosine kinase, sphingosine-1-phosphate, and apoptosis. Biochimica Et Biophysica Acta. 1585: 193-201 |
| Vann LR, Payne SG, Edsall LC, et al. (2002) Involvement of sphingosine kinase in TNF-alpha-stimulated tetrahydrobiopterin biosynthesis in C6 glioma cells. The Journal of Biological Chemistry. 277: 12649-56 |
| Payne SG, Brindley DN, Guilbert LJ. (1999) Epidermal growth factor inhibits ceramide-induced apoptosis and lowers ceramide levels in primary placental trophoblasts. Journal of Cellular Physiology. 180: 263-70 |