Christopher Overend, Ph.D.

Affiliations: 
2011 University of Connecticut, Storrs, CT, United States 
Area:
Virology Biology, Animal Pathology Agriculture
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"Christopher Overend"

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A E. Garmendia grad student 2011 University of Connecticut
 (Mechanisms of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Control of the Host Innate Immune Response.)
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Publications

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Cao D, Sooryanarain H, Yugo DM, et al. (2018) Evaluation of the pathogenicity of mammalian orthoreovirus type 3 (MRV3) in germ-free gnotobiotic pigs and of the efficacy of an inactivated vaccine against MRV3 infection in neonatal conventional piglets. Veterinary Microbiology. 224: 23-30
Yugo DM, Heffron CL, Ryu J, et al. (2018) Infection dynamics of hepatitis E virus in wild-type and immunoglobulin heavy chain knockout J (-/-) gnotobiotic piglets. Journal of Virology
Cao QM, Ni YY, Cao D, et al. (2018) Recombinant porcine reproductive and respiratory syndrome virus expressing membrane-bound IL-15 as immunomodulatory adjuvant enhances NK and γδ T cell responses and confers heterologous protection. Journal of Virology
Subramaniam S, Overend C, Yugo DM, et al. (2018) Isolation of Peripheral Blood CD8 T Cells Specific to Porcine Reproductive and Respiratory Syndrome Virus Utilizing Porcine CD137 Activation Marker. Viral Immunology
Cao D, Cao QM, Subramaniam S, et al. (2017) Pig model mimicking chronic hepatitis E virus infection in immunocompromised patients to assess immune correlates during chronicity. Proceedings of the National Academy of Sciences of the United States of America
Tian D, Cao D, Lynn Heffron C, et al. (2017) Enhancing heterologous protection in pigs vaccinated with chimeric porcine reproductive and respiratory syndrome virus containing the full-length sequences of shuffled structural genes of multiple heterologous strains. Vaccine
Overend CC, Cui J, Grubman MJ, et al. (2016) The activation of the IFNβ induction/signaling pathway in porcine alveolar macrophages by porcine reproductive and respiratory syndrome virus is variable. Veterinary Research Communications
Subramaniam S, Cao D, Tian D, et al. (2016) Efficient priming of CD4 T cells by Langerin-expressing dendritic cells targeted with porcine epidemic diarrhea virus spike protein domains in pigs. Virus Research
Tian D, Ni YY, Zhou L, et al. (2015) Chimeric porcine reproductive and respiratory syndrome virus containing shuffled multiple envelope genes confers cross-protection in pigs. Virology. 485: 402-13
Subramaniam S, Piñeyro P, Tian D, et al. (2014) In vivo targeting of porcine reproductive and respiratory syndrome virus antigen through porcine DC-SIGN to dendritic cells elicits antigen-specific CD4T cell immunity in pigs. Vaccine. 32: 6768-75
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