Jack Hutcheson, Ph.D.

Affiliations: 
2008 Saint Louis University, St. Louis, MO, United States 
Area:
Cell Biology
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"Jack Hutcheson"

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Harris Perlman grad student 2008 Saint Louis University
 (Bim: A central regulator of hematopoietic development and a suppressor of autoimmunity.)
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Publications

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Wu T, Marakkath B, Ye Y, et al. (2020) Curcumin Attenuates Both Acute and Chronic Immune Nephritis. International Journal of Molecular Sciences. 21
Tsai F, Homan PJ, Agrawal H, et al. (2017) Bim suppresses the development of SLE by limiting myeloid inflammatory responses. The Journal of Experimental Medicine
Knudsen ES, Hutcheson J, Vail P, et al. (2017) Biological specificity of CDK4/6 inhibitors: dose response relationship, in vivo signaling, and composite response signature. Oncotarget
Orme JJ, Du Y, Vanarsa K, et al. (2016) Heightened Cleavage of Axl Receptor Tyrosine Kinase by ADAM metalloproteases may contribute to disease pathogenesis in SLE. Clinical Immunology (Orlando, Fla.)
Cuda CM, Misharin AV, Khare S, et al. (2015) Conditional deletion of caspase-8 in macrophages alters macrophage activation in a RIPK-dependent manner. Arthritis Research & Therapy. 17: 291
Hutcheson J. (2015) Adipokines influence the inflammatory balance in autoimmunity. Cytokine. 75: 272-9
Hutcheson J, Bourgo RJ, Balaji U, et al. (2014) Retinoblastoma protein potentiates the innate immune response in hepatocytes: significance for hepatocellular carcinoma. Hepatology (Baltimore, Md.). 60: 1231-40
Cuda CM, Misharin AV, Gierut AK, et al. (2014) Caspase-8 acts as a molecular rheostat to limit RIPK1- and MyD88-mediated dendritic cell activation. Journal of Immunology (Baltimore, Md. : 1950). 192: 5548-60
Hutcheson J, Vanarsa K, Bashmakov A, et al. (2012) Modulating proximal cell signaling by targeting Btk ameliorates humoral autoimmunity and end-organ disease in murine lupus. Arthritis Research & Therapy. 14: R243
Li L, Nukala S, Du Y, et al. (2012) Murine lupus strains differentially model unique facets of human lupus serology. Clinical and Experimental Immunology. 168: 178-85
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