Wen-Hwa Lee

Affiliations: 
Biomedical Sciences - Ph.D. University of California, Irvine, Irvine, CA 
Area:
Molecular Biology, Biochemistry, Microbiology Biology, Genetics
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"Wen-Hwa Lee"

Parents

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Peter H. Duesberg grad student (Neurotree)

Children

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Bryan Ngo research assistant UC Irvine School of Medicine (Chemistry Tree)
Saori Furuta grad student 2007 UC Irvine
Lily Khidr grad student 2008 UC Irvine
Randy L. Wei grad student 2010 UC Irvine
Xuning E. Guo grad student 2011 UC Irvine
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Publications

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Huang SC, Wei PC, Hwang-Verslues WW, et al. (2017) TGF-β1 secreted by Tregs in lymph nodes promotes breast cancer malignancy via up-regulation of IL-17RB. Embo Molecular Medicine
Chen JY, Tsai WS, Shao HJ, et al. (2016) Sensitive and Specific Biomimetic Lipid Coated Microfluidics to Isolate Viable Circulating Tumor Cells and Microemboli for Cancer Detection. Plos One. 11: e0149633
Kao SH, Wu KJ, Lee WH. (2016) Hypoxia, Epithelial-Mesenchymal Transition, and TET-Mediated Epigenetic Changes. Journal of Clinical Medicine. 5
Lee WH, Wu HH, Huang CK. (2015) Targeting interleukin-17 receptors. Oncotarget. 6: 18244-5
Zhu J, Chen H, Guo XE, et al. (2015) Synthesis, molecular modeling, and biological evaluation of novel RAD51 inhibitors. European Journal of Medicinal Chemistry. 96: 196-208
Wu HH, Hwang-Verslues WW, Lee WH, et al. (2015) Targeting IL-17B-IL-17RB signaling with an anti-IL-17RB antibody blocks pancreatic cancer metastasis by silencing multiple chemokines. The Journal of Experimental Medicine. 212: 333-49
Hu CM, Zhu J, Guo XE, et al. (2015) Novel small molecules disrupting Hec1/Nek2 interaction ablate tumor progression by triggering Nek2 degradation through a death-trap mechanism. Oncogene. 34: 1220-30
Wang DD, Guo XE, Modrek AS, et al. (2014) Helicase SUV3, polynucleotide phosphorylase, and mitochondrial polyadenylation polymerase form a transient complex to modulate mitochondrial mRNA polyadenylated tail lengths in response to energetic changes. The Journal of Biological Chemistry. 289: 16727-35
Guo XE, Ngo B, Modrek AS, et al. (2014) Targeting tumor suppressor networks for cancer therapeutics. Current Drug Targets. 15: 2-16
Ngo B, Hu CM, Guo XE, et al. (2013) Complementary interhelical interactions between three buried Glu-Lys pairs within three heptad repeats are essential for Hec1-Nuf2 heterodimerization and mitotic progression. The Journal of Biological Chemistry. 288: 34403-13
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