Xuning E. Guo, Ph.D.
Affiliations: | 2011 | Biomedical Sciences - Ph.D. | University of California, Irvine, Irvine, CA |
Area:
Molecular Biology, Biochemistry, Microbiology Biology, GeneticsGoogle:
"Xuning Guo"Parents
Sign in to add mentor| Wen-Hwa Lee | grad student | 2011 | UC Irvine | |
| (Role of SUV3 in Maintaining Yeast Mitochondrial Homeostasis.) | ||||
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Publications
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| Zhu J, Chen H, Guo XE, et al. (2015) Synthesis, molecular modeling, and biological evaluation of novel RAD51 inhibitors. European Journal of Medicinal Chemistry. 96: 196-208 |
| Hu CM, Zhu J, Guo XE, et al. (2015) Novel small molecules disrupting Hec1/Nek2 interaction ablate tumor progression by triggering Nek2 degradation through a death-trap mechanism. Oncogene. 34: 1220-30 |
| Wang DD, Guo XE, Modrek AS, et al. (2014) Helicase SUV3, polynucleotide phosphorylase, and mitochondrial polyadenylation polymerase form a transient complex to modulate mitochondrial mRNA polyadenylated tail lengths in response to energetic changes. The Journal of Biological Chemistry. 289: 16727-35 |
| Guo XE, Ngo B, Modrek AS, et al. (2014) Targeting tumor suppressor networks for cancer therapeutics. Current Drug Targets. 15: 2-16 |
| Ngo B, Hu CM, Guo XE, et al. (2013) Complementary interhelical interactions between three buried Glu-Lys pairs within three heptad repeats are essential for Hec1-Nuf2 heterodimerization and mitotic progression. The Journal of Biological Chemistry. 288: 34403-13 |
| Chen PL, Chen CF, Chen Y, et al. (2013) Mitochondrial genome instability resulting from SUV3 haploinsufficiency leads to tumorigenesis and shortened lifespan. Oncogene. 32: 1193-201 |
| Guo XE, Chen CF, Wang DD, et al. (2011) Uncoupling the roles of the SUV3 helicase in maintenance of mitochondrial genome stability and RNA degradation. The Journal of Biological Chemistry. 286: 38783-94 |
| Wu G, Zhou L, Khidr L, et al. (2008) A novel role of the chromokinesin Kif4A in DNA damage response. Cell Cycle (Georgetown, Tex.). 7: 2013-20 |