Hazem E. Ghoneim, Ph.D.
Affiliations: | 2013 | Microbial Pathogenesis, Immunology, and Inflammation | University of Tennessee Health Science Center, Memphis, TN, United States |
Area:
Microbiology Biology, Immunology, Virology BiologyGoogle:
"Hazem Ghoneim"Parents
Sign in to add mentor| Jonathan A. McCullers | grad student | 2013 | UTHSC | |
| (A Novel Mechanism of Enhanced Susceptibility to Bacterial Pneumonia in Influenza-infected Hosts.) | ||||
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Publications
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| Read KA, Jones DM, Pokhrel S, et al. (2023) Aiolos represses CD4 T cell cytotoxic programming via reciprocal regulation of T transcription factors and IL-2 sensitivity. Nature Communications. 14: 1652 |
| Soerens AG, Künzli M, Quarnstrom CF, et al. (2023) Functional T cells are capable of supernumerary cell division and longevity. Nature |
| Saadey AA, Yousif A, Osborne N, et al. (2022) Rebalancing TGFβ1/BMP signals in exhausted T cells unlocks responsiveness to immune checkpoint blockade therapy. Nature Immunology |
| LeMessurier KS, Rooney R, Ghoneim HE, et al. (2020) Influenza A virus directly modulates mouse eosinophil responses. Journal of Leukocyte Biology |
| Abdelsamed HA, Zebley CC, Nguyen H, et al. (2020) Beta cell-specific CD8 T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes. Nature Immunology |
| Fonseca R, Beura LK, Quarnstrom CF, et al. (2020) Developmental plasticity allows outside-in immune responses by resident memory T cells. Nature Immunology |
| Alfei F, Kanev K, Hofmann M, et al. (2019) TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection. Nature |
| Ghoneim HE, Fan Y, Moustaki A, et al. (2019) Abstract A189: Targeting T-cell epigenetic programs to enhance the efficacy of immune checkpoint blockade Cancer Immunology Research. 7 |
| Ghoneim HE, Fan Y, Moustaki A, et al. (2018) Abstract A26: De novo epigenetic programming restrains PD-1 blockade-mediated T cell rejuvenation Cancer Immunology Research. 6 |
| Youngblood B, Hale JS, Kissick HT, et al. (2017) Effector CD8 T cells dedifferentiate into long-lived memory cells. Nature |