Arielle Butts, Ph.D.

Affiliations: 
2013 School of Arts and Sciences University of Rochester, Rochester, NY 
Area:
Molecular Chemistry, Microbiology Biology, Organic Chemistry
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"Arielle Butts"

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Damian Krysan grad student 2013 Rochester
 (Repurposing Triphenylethylene Estrogen Receptor Antagonists as Anticryptococcal Agents.)
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Publications

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Njikan S, Ahmed S, Manning A, et al. (2022) Chemical Exploration of a Highly Selective Scaffold with Activity against Intracellular . Microbiology Spectrum. e0116122
Butts A, Reitler P, Nishimoto AT, et al. (2019) A systematic screen reveals a diverse collection of medications induce antifungal resistance in species. Antimicrobial Agents and Chemotherapy
Luna-Tapia A, Butts A, Palmer GE. (2018) Loss of C-5 sterol desaturase activity in - azole resistance or merely trailing growth? Antimicrobial Agents and Chemotherapy
Butts A, Reitler P, Ge W, et al. (2018) Commonly used oncology drugs decrease antifungal effectiveness against and species. Antimicrobial Agents and Chemotherapy
Butts A, DeJarnette C, Peters TL, et al. (2017) Target Abundance-Based Fitness Screening (TAFiS) Facilitates Rapid Identification of Target-Specific and Physiologically Active Chemical Probes. Msphere. 2
Butts A, Palmer GE, Rogers PD. (2016) Antifungal adjuvants: preserving and extending the antifungal arsenal. Virulence. 0
Butts A, Martin JA, DiDone L, et al. (2015) Structure-activity relationships for the antifungal activity of selective estrogen receptor antagonists related to tamoxifen. Plos One. 10: e0125927
Brown JC, Nelson J, VanderSluis B, et al. (2014) Unraveling the biology of a fungal meningitis pathogen using chemical genetics. Cell. 159: 1168-87
Butts A, Koselny K, Chabrier-Roselló Y, et al. (2014) Estrogen receptor antagonists are anti-cryptococcal agents that directly bind EF hand proteins and synergize with fluconazole in vivo. Mbio. 5: e00765-13
Butts A, DiDone L, Koselny K, et al. (2013) A repurposing approach identifies off-patent drugs with fungicidal cryptococcal activity, a common structural chemotype, and pharmacological properties relevant to the treatment of cryptococcosis. Eukaryotic Cell. 12: 278-87
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