Roxana M. Coman, Ph.D.
Affiliations: | 2007 | University of Florida, Gainesville, Gainesville, FL, United States |
Area:
Microbiology BiologyGoogle:
"Roxana Coman"Parents
Sign in to add mentor| Ben M. Dunn | grad student | 2007 | UF Gainesville | |
| (The contribution of the naturally occurring polymorphisms in altering the biochemical and structural characteristics of HIV -1 subtype C protease.) | ||||
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| Mavian C, Coman RM, Zhang X, et al. (2021) Molecular Docking-Based Screening for Novel Inhibitors of the Human Immunodeficiency Virus Type 1 Protease that Effectively Reduce the Viral Replication in Human Cells. Journal of Aids & Clinical Research. 12 |
| Robbins AH, Coman RM, Bracho-Sanchez E, et al. (2010) Structure of the unbound form of HIV-1 subtype A protease: comparison with unbound forms of proteases from other HIV subtypes. Acta Crystallographica. Section D, Biological Crystallography. 66: 233-42 |
| Ho SK, Perez EE, Rose SL, et al. (2009) Genetic determinants in HIV-1 Gag and Env V3 are related to viral response to combination antiretroviral therapy with a protease inhibitor. Aids (London, England). 23: 1631-40 |
| Ho SK, Coman RM, Bunger JC, et al. (2008) Drug-associated changes in amino acid residues in Gag p2, p7(NC), and p6(Gag)/p6(Pol) in human immunodeficiency virus type 1 (HIV-1) display a dominant effect on replicative fitness and drug response. Virology. 378: 272-81 |
| Coman RM, Robbins AH, Goodenow MM, et al. (2008) High-resolution structure of unbound human immunodeficiency virus 1 subtype C protease: implications of flap dynamics and drug resistance. Acta Crystallographica. Section D, Biological Crystallography. 754-63 |
| Coman RM, Robbins AH, Fernandez MA, et al. (2008) The contribution of naturally occurring polymorphisms in altering the biochemical and structural characteristics of HIV-1 subtype C protease. Biochemistry. 47: 731-43 |
| Coman RM, Robbins A, Goodenow MM, et al. (2007) Expression, purification and preliminary X-ray crystallographic studies of the human immunodeficiency virus 1 subtype C protease. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 63: 320-3 |
| Clemente JC, Coman RM, Thiaville MM, et al. (2006) Analysis of HIV-1 CRF_01 A/E protease inhibitor resistance: structural determinants for maintaining sensitivity and developing resistance to atazanavir. Biochemistry. 45: 5468-77 |