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Simon J. Davis, BSc, PhD

Affiliations: 
1995- Radcliffe Department of Medicine University of Oxford, Oxford, United Kingdom 
Area:
T cell biology, structural immunology, immune checkpoints
Website:
http://davislab-oxford.org/
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"Simon Davis"

Children

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Victoria Junghans grad student (Chemistry Tree)
Alexander M. Mørch grad student 2019- Oxford
Edward Jenkins grad student 2016-2020 Oxford
Robert Donat grad student 2018-2022 Oxford
Martin Fellermeyer grad student 2018-2022 Oxford
João Ferreira Fernandes grad student 2018-2022 Oxford
Caitlin O'Brien-Ball grad student 2018-2022 Oxford
Mateusz Kotowski grad student 2019-2023 Oxford
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Publications

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Leithner A, Staufer O, Mitra T, et al. (2025) Solution structure and synaptic analyses reveal determinants of bispecific T cell engager potency. Proceedings of the National Academy of Sciences of the United States of America. 122: e2425781122
Damianou A, Jones HBL, Grigoriou A, et al. (2025) Integrative proximal-ubiquitomics profiling for deubiquitinase substrate discovery applied to USP30. Cell Chemical Biology
Sun B, Fernandes D, Soltys J, et al. (2025) Permissive central tolerance plus defective peripheral checkpoints license pathogenic memory B cells in CASPR2-antibody encephalitis. Science Advances. 11: eadr9986
Lui Y, Ferreira Fernandes J, Vuong MT, et al. (2025) The Structural Biology of T-Cell Antigen Detection at Close Contacts. Immunological Reviews. 331: e70014
Sun B, Fernandes D, Kienzler AK, et al. (2025) Permissive central tolerance plus defective peripheral checkpoints licence pathogenic memory B cells in CASPR2-antibody encephalitis. Biorxiv : the Preprint Server For Biology
Quinn J, Salman A, Paluch C, et al. (2024) Single-cell transcriptomic analysis of retinal immune regulation and blood-retinal barrier function during experimental autoimmune uveitis. Scientific Reports. 14: 20033
Gully BS, Ferreira Fernandes J, Gunasinghe SD, et al. (2024) Structure of a fully assembled γδ T-cell antigen receptor. Nature
Santos RF, de Sousa Linhares A, Steinberger P, et al. (2024) The CD6 interactome orchestrates ligand-independent T cell inhibitory signaling. Cell Communication and Signaling : Ccs. 22: 286
Gupta T, Antanaviciute A, Hyun-Jung Lee C, et al. (2024) Tracking in situ checkpoint inhibitor-bound target T cells in patients with checkpoint-induced colitis. Cancer Cell. 42: 797-814.e15
Lippert AH, Paluch C, Gaglioni M, et al. (2024) Antibody agonists trigger immune receptor signaling through local exclusion of receptor-type protein tyrosine phosphatases. Immunity. 57: 256-270.e10
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