Balbino Alarcón
Affiliations: | Centro de Biología Molecular. (CSIC-UAM). Madrid. Spain |
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| Martinez-Martin N, Alarcon B. (2023) Physiological and therapeutic relevance of T cell receptor-mediated antigen trogocytosis. Biomedical Journal. 100630 |
| Boccasavia VL, Bovolenta ER, Villanueva A, et al. (2021) Antigen presentation between T cells drives Th17 polarization under conditions of limiting antigen. Cell Reports. 34: 108861 |
| Alarcon B, Borroto A. (2020) Small molecule AX-024 targets T cell receptor signaling by disrupting CD3ε-Nck interaction. The Journal of Biological Chemistry. 295: 10076 |
| Martín-Leal A, Blanco R, Casas J, et al. (2020) CCR5 deficiency impairs CD4 T-cell memory responses and antigenic sensitivity through increased ceramide synthesis. The Embo Journal. e104749 |
| Merino-Cortés SV, Gardeta SR, Roman-Garcia S, et al. (2020) Diacylglycerol kinase ζ promotes actin cytoskeleton remodeling and mechanical forces at the B cell immune synapse. Science Signaling. 13 |
| Schamel WW, Alarcon B, Minguet S. (2019) The TCR is an allosterically regulated macromolecular machinery changing its conformation while working. Immunological Reviews. 291: 8-25 |
| Martínez-Riaño A, Bovolenta ER, Boccasavia VL, et al. (2019) RRAS2 shapes the TCR repertoire by setting the threshold for negative selection. The Journal of Experimental Medicine. 216: 2427-2447 |
| Martínez-Riaño A, Bovolenta ER, Mendoza P, et al. (2018) Antigen phagocytosis by B cells is required for a potent humoral response. Embo Reports |
| Martín-Blanco NM, Blanco R, Alda-Catalinas C, et al. (2018) A window of opportunity for cooperativity in the T Cell Receptor. Nature Communications. 9: 2618-2618 |
| Mendoza P, Martínez-Martín N, Bovolenta ER, et al. (2018) R-Ras2 is required for germinal center formation to aid B cells during energetically demanding processes. Science Signaling. 11 |