Maudry Laurent-Rolle, Ph.D.

Affiliations: 
2011 Microbiology Mount Sinai School of Medicine, New York, NY 
Area:
Virology Biology, Immunology
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"Maudry Laurent-Rolle"

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Adolfo Garcia-Sastre grad student 2011 Mount Sinai
 (Characterization of the molecular basis of the interferon-antagonist function of YFV NS5.)
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Publications

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Pawlak JB, Hsu JC, Xia H, et al. (2023) CMPK2 restricts Zika virus replication by inhibiting viral translation. Plos Pathogens. 19: e1011286
Arshad N, Laurent-Rolle M, Ahmed WS, et al. (2022) SARS-CoV-2 accessory proteins ORF7a and ORF3a use distinct mechanisms to down-regulate MHC-I surface expression. Proceedings of the National Academy of Sciences of the United States of America. 120: e2208525120
Hsu JC, Laurent-Rolle M, Pawlak JB, et al. (2022) Viperin triggers ribosome collision-dependent translation inhibition to restrict viral replication. Molecular Cell
Hsu JC, Laurent-Rolle M, Pawlak JB, et al. (2021) Translational shutdown and evasion of the innate immune response by SARS-CoV-2 NSP14 protein. Proceedings of the National Academy of Sciences of the United States of America. 118
Laurent-Rolle M, Morrison J. (2019) The Role of NS5 Protein in Determination of Host Cell Range for Yellow Fever Virus. Dna and Cell Biology
Miorin L, Laurent-Rolle M, Pisanelli G, et al. (2019) Host-specific NS5 ubiquitination determines yellow fever virus tropism. Journal of Virology
Pisanelli G, Laurent-Rolle M, Manicassamy B, et al. (2015) La Piedad Michoacán Mexico Virus V protein antagonizes type I interferon response by binding STAT2 protein and preventing STATs nuclear translocation. Virus Research
Laurent-Rolle M, Morrison J, Rajsbaum R, et al. (2014) The interferon signaling antagonist function of yellow fever virus NS5 protein is activated by type I interferon. Cell Host & Microbe. 16: 314-27
Rajsbaum R, Versteeg GA, Schmid S, et al. (2014) Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response. Immunity. 40: 880-95
Morrison J, Laurent-Rolle M, Maestre AM, et al. (2013) Dengue virus co-opts UBR4 to degrade STAT2 and antagonize type I interferon signaling. Plos Pathogens. 9: e1003265
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