| Year |
Citation |
Score |
| 2012 |
Caroli A, Simeoni S, Lepore R, Tramontano A, Via A. Investigation of a potential mechanism for the inhibition of SmTGR by Auranofin and its implications for Plasmodium falciparum inhibition. Biochemical and Biophysical Research Communications. 417: 576-81. PMID 22177949 DOI: 10.1016/J.Bbrc.2011.12.009 |
0.72 |
|
| 2011 |
Lepore R, Simeoni S, Raimondo D, Caroli A, Tramontano A, Via A. Identification of the Schistosoma mansoni molecular target for the antimalarial drug artemether. Journal of Chemical Information and Modeling. 51: 3005-16. PMID 21995318 DOI: 10.1021/Ci2001764 |
0.72 |
|
| 2011 |
Valente S, Tardugno M, Conte M, Cirilli R, Perrone A, Ragno R, Simeoni S, Tramontano A, Massa S, Nebbioso A, Miceli M, Franci G, Brosch G, Altucci L, Mai A. Novel cinnamyl hydroxyamides and 2-aminoanilides as histone deacetylase inhibitors: apoptotic induction and cytodifferentiation activity. Chemmedchem. 6: 698-712. PMID 21374822 DOI: 10.1002/Cmdc.201000535 |
0.732 |
|
| 2010 |
Castellano S, Milite C, Ragno R, Simeoni S, Mai A, Limongelli V, Novellino E, Bauer I, Brosch G, Spannhoff A, Cheng D, Bedford MT, Sbardella G. Design, synthesis and biological evaluation of carboxy analogues of arginine methyltransferase inhibitor 1 (AMI-1). Chemmedchem. 5: 398-414. PMID 20091730 DOI: 10.1002/Cmdc.200900459 |
0.678 |
|
| 2009 |
Musmuca I, Simeoni S, Caroli A, Ragno R. Small-molecule interferon inducers. Toward the comprehension of the molecular determinants through ligand-based approaches. Journal of Chemical Information and Modeling. 49: 1777-86. PMID 19499914 DOI: 10.1021/Ci900065A |
0.621 |
|
| 2009 |
Mai A, Valente S, Nebbioso A, Simeoni S, Ragno R, Massa S, Brosch G, De Bellis F, Manzo F, Altucci L. New pyrrole-based histone deacetylase inhibitors: binding mode, enzyme- and cell-based investigations. The International Journal of Biochemistry & Cell Biology. 41: 235-47. PMID 18834955 DOI: 10.1016/J.Biocel.2008.09.002 |
0.749 |
|
| 2008 |
Ragno R, Simeoni S, Rotili D, Caroli A, Botta G, Brosch G, Massa S, Mai A. Class II-selective histone deacetylase inhibitors. Part 2: alignment-independent GRIND 3-D QSAR, homology and docking studies. European Journal of Medicinal Chemistry. 43: 621-32. PMID 17698257 DOI: 10.1016/J.Ejmech.2007.05.004 |
0.73 |
|
| 2007 |
Mai A, Artico M, Rotili D, Tarantino D, Clotet-Codina I, Armand-Ugón M, Ragno R, Simeoni S, Sbardella G, Nawrozkij MB, Samuele A, Maga G, Esté JA. Synthesis and biological properties of novel 2-aminopyrimidin-4(3H)-ones highly potent against HIV-1 mutant strains. Journal of Medicinal Chemistry. 50: 5412-24. PMID 17910429 DOI: 10.1021/Jm070811E |
0.605 |
|
| 2007 |
Mai A, Valente S, Cheng D, Perrone A, Ragno R, Simeoni S, Sbardella G, Brosch G, Nebbioso A, Conte M, Altucci L, Bedford MT. Synthesis and biological validation of novel synthetic histone/protein methyltransferase inhibitors. Chemmedchem. 2: 987-91. PMID 17458842 DOI: 10.1002/Cmdc.200700023 |
0.65 |
|
| 2007 |
Ragno R, Simeoni S, Castellano S, Vicidomini C, Mai A, Caroli A, Tramontano A, Bonaccini C, Trojer P, Bauer I, Brosch G, Sbardella G. Small molecule inhibitors of histone arginine methyltransferases: homology modeling, molecular docking, binding mode analysis, and biological evaluations. Journal of Medicinal Chemistry. 50: 1241-53. PMID 17323938 DOI: 10.1021/Jm061213N |
0.654 |
|
| 2006 |
Mai A, Massa S, Rotili D, Simeoni S, Ragno R, Botta G, Nebbioso A, Miceli M, Altucci L, Brosch G. Synthesis and biological properties of novel, uracil-containing histone deacetylase inhibitors. Journal of Medicinal Chemistry. 49: 6046-56. PMID 17004718 DOI: 10.1021/Jm0605536 |
0.732 |
|
| 2006 |
Mai A, Massa S, Valente S, Simeoni S, Ragno R, Bottoni P, Scatena R, Brosch G. Aroyl-pyrrolyl hydroxyamides: influence of pyrrole C4-phenylacetyl substitution on histone deacetylase inhibition. Chemmedchem. 1: 225-37. PMID 16892355 DOI: 10.1002/Cmdc.200500015 |
0.733 |
|
| 2006 |
Ragno R, Simeoni S, Valente S, Massa S, Mai A. 3-D QSAR studies on histone deacetylase inhibitors. A GOLPE/GRID approach on different series of compounds. Journal of Chemical Information and Modeling. 46: 1420-30. PMID 16711762 DOI: 10.1021/Ci050556B |
0.721 |
|
| 2005 |
Mai A, Massa S, Lavu S, Pezzi R, Simeoni S, Ragno R, Mariotti FR, Chiani F, Camilloni G, Sinclair DA. Design, synthesis, and biological evaluation of sirtinol analogues as class III histone/protein deacetylase (Sirtuin) inhibitors. Journal of Medicinal Chemistry. 48: 7789-95. PMID 16302818 DOI: 10.1021/Jm050100L |
0.731 |
|
| 2005 |
Mai A, Massa S, Pezzi R, Simeoni S, Rotili D, Nebbioso A, Scognamiglio A, Altucci L, Loidl P, Brosch G. Class II (IIa)-selective histone deacetylase inhibitors. 1. Synthesis and biological evaluation of novel (aryloxopropenyl)pyrrolyl hydroxyamides Journal of Medicinal Chemistry. 48: 3344-3353. PMID 15857140 DOI: 10.1021/Jm049002A |
0.639 |
|
| 2005 |
Mai A, Massa S, Rotili D, Cerbara I, Valente S, Pezzi R, Simeoni S, Ragna R. Histone deacetylation in epigenetics: An attractive target for anticancer therapy Medicinal Research Reviews. 25: 261-309. PMID 15717297 DOI: 10.1002/Med.20024 |
0.619 |
|
| 2005 |
Mai A, Massa S, Rotili D, Cerbara I, Valente S, Pezzi R, Simeoni S, Ragno R. Histone Deacetylation in Epigenetics: An Attractive Target for Anticancer Therapy Cheminform. 36. DOI: 10.1002/CHIN.200528271 |
0.649 |
|
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