| Year |
Citation |
Score |
| 2022 |
Garrison AT, Orsi DL, Capstick RA, Whomble D, Li J, Carter TR, Felts AS, Vinson PN, Rodriguez AL, Han A, Hajari K, Cho HP, Teal LB, Ragland MG, Ghamari-Langroudi M, et al. Development of : A Potent, Highly Selective, and Systemically Active Orthosteric Antagonist of the M Muscarinic Acetylcholine Receptor for the Treatment of Opioid Use Disorder. Journal of Medicinal Chemistry. PMID 35417155 DOI: 10.1021/acs.jmedchem.2c00192 |
0.349 |
|
| 2022 |
Huigens RW, Brummel BR, Tenneti S, Garrison AT, Xiao T. Pyrazine and Phenazine Heterocycles: Platforms for Total Synthesis and Drug Discovery. Molecules (Basel, Switzerland). 27. PMID 35164376 DOI: 10.3390/molecules27031112 |
0.618 |
|
| 2019 |
Gould RW, Gunter BW, Bubser M, Matthews RT, Teal LB, Ragland MG, Bridges TM, Garrison AT, Winder DG, Lindsley CW, Jones CK. Acute Negative Allosteric Modulation of M Muscarinic Acetylcholine Receptors Inhibits Oxycodone Self-Administration and Cue-Induced Reactivity with no effect on Antinociception. Acs Chemical Neuroscience. PMID 31268669 DOI: 10.1021/Acschemneuro.9B00274 |
0.409 |
|
| 2019 |
Childress ES, Garrison AT, Sheldon JR, Skaar EP, Lindsley CW. Total synthesis of hinduchelins A-D, stereochemical revision of hinduchelin A, and biological evaluation of natural and unnatural analogs. The Journal of Organic Chemistry. PMID 31039303 DOI: 10.1021/Acs.Joc.9B00391 |
0.422 |
|
| 2019 |
Abouelhassan Y, Garrison A, Yang H, Chavez Riveros A, Burch G, Huigens Iii RW. Recent Progress in Natural Product-Inspired Programs Aimed at Addressing Antibiotic Resistance and Tolerance. Journal of Medicinal Chemistry. PMID 30951303 DOI: 10.1021/Acs.Jmedchem.9B00370 |
0.556 |
|
| 2019 |
Garrison AT, Childress ES, Davis DC, Lindsley CW. Preparation of 1,5-Dihydropyrazolo[3',4':5,6]pyrano[3,4- b]pyridines via a Microwave-Assisted, Palladium-Catalyzed Regioselective C-H Heteroarylation of Electron-Rich Pyrazoles. The Journal of Organic Chemistry. PMID 30807155 DOI: 10.1021/Acs.Joc.9B00144 |
0.424 |
|
| 2018 |
Bender AM, Garrison AT, Lindsley CW. The Muscarinic Acetylcholine Receptor M5: Therapeutic Implications and Allosteric Modulation. Acs Chemical Neuroscience. PMID 30280567 DOI: 10.1021/Acschemneuro.8B00481 |
0.351 |
|
| 2018 |
Garrison AT, Abouelhassan Y, Kallifidas D, Tan H, Kim YS, Jin S, Luesch H, Huigens Iii RW. An Efficient Buchwald-Hartwig/Reductive Cyclization for the Scaffold Diversification of Halogenated Phenazines: Potent Antibacterial Targeting, Biofilm Eradication and Prodrug Exploration. Journal of Medicinal Chemistry. PMID 29638121 DOI: 10.1021/Acs.Jmedchem.7B01903 |
0.606 |
|
| 2017 |
Garrison AT, Abouelhassan Y, Yang H, Yousaf HH, Nguyen TJ, Huigens Iii RW. Microwave-enhanced Friedländer synthesis for the rapid assembly of halogenated quinolines with antibacterial and biofilm eradication activities against drug resistant and tolerant bacteria. Medchemcomm. 8: 720-724. PMID 30108790 DOI: 10.1039/C6Md00381H |
0.533 |
|
| 2016 |
Garrison AT, Huigens Iii RW. Eradicating Bacterial Biofilms with Natural Products and Their Inspired Analogues that Operate Through Unique Mechanisms. Current Topics in Medicinal Chemistry. PMID 27966398 |
0.476 |
|
| 2016 |
Zuo R, Garrison AT, Basak A, Zhang P, Huigens RW, Ding Y. In vitro antifungal and antibiofilm activities of halogenated quinoline analogues against Candida albicans and Cryptococcus neoformans. International Journal of Antimicrobial Agents. PMID 27256584 DOI: 10.1016/J.Ijantimicag.2016.04.019 |
0.68 |
|
| 2016 |
Garrison AT, Abouelhassan Y, Norwood VM, Kallifidas D, Bai F, Nguyen MT, Rolfe M, Burch GM, Jin S, Luesch H, Huigens Iii RW. Structure-Activity Relationships of a Diverse Class of Halogenated Phenazines that Targets Persistent, Antibiotic-Tolerant Bacterial Biofilms and Mycobacterium tuberculosis. Journal of Medicinal Chemistry. PMID 27018907 DOI: 10.1021/Acs.Jmedchem.5B02004 |
0.582 |
|
| 2015 |
Garrison AT, Abouelhassan Y, Kallifidas D, Bai F, Ukhanova M, Mai V, Jin S, Luesch H, Huigens RW. Halogenated Phenazines that Potently Eradicate Biofilms, MRSA Persister Cells in Non-Biofilm Cultures, and Mycobacterium tuberculosis. Angewandte Chemie (International Ed. in English). PMID 26480852 DOI: 10.1002/Anie.201508155 |
0.697 |
|
| 2015 |
Abouelhassan Y, Garrison AT, Bai F, Norwood VM, Nguyen MT, Jin S, Huigens RW. A Phytochemical-Halogenated Quinoline Combination Therapy Strategy for the Treatment of Pathogenic Bacteria. Chemmedchem. 10: 1157-62. PMID 25982664 DOI: 10.1002/Cmdc.201500179 |
0.701 |
|
| 2015 |
Garrison AT, Bai F, Abouelhassan Y, Paciaroni NG, Jin S, Huigens RW. Bromophenazine derivatives with potent inhibition, dispersion and eradication activities against Staphylococcus aureus biofilms Rsc Advances. 5: 1120-1124. DOI: 10.1039/C4Ra08728C |
0.719 |
|
| 2014 |
Abouelhassan Y, Garrison AT, Burch GM, Wong W, Norwood VM, Huigens RW. Discovery of quinoline small molecules with potent dispersal activity against methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis biofilms using a scaffold hopping strategy. Bioorganic & Medicinal Chemistry Letters. 24: 5076-80. PMID 25264073 DOI: 10.1016/J.Bmcl.2014.09.009 |
0.713 |
|
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