Xuewen Pan, Ph.D.

Affiliations: 
2001 Duke University, Durham, NC 
Area:
Sex in Fungi, Signaling, Pathogenesis, Cryptococcus,
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"Xuewen Pan"

Parents

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Joseph Heitman grad student 2001 Tango Therapeutics
 (A cAMP -dependent protein kinase A pathway controls pseudohyphal differentiation in Saccharomyces cerevisiae.)
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Publications

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Chen X, Niu H, Yu Y, et al. (2016) Enrichment of Cdk1-cyclins at DNA double-strand breaks stimulates Fun30 phosphorylation and DNA end resection. Nucleic Acids Research
Ravu RR, Chen YL, Jacob MR, et al. (2013) Synthesis and antifungal activities of miltefosine analogs. Bioorganic & Medicinal Chemistry Letters. 23: 4828-31
Huang Z, Srinivasan S, Zhang J, et al. (2012) Discovering thiamine transporters as targets of chloroquine using a novel functional genomics strategy. Plos Genetics. 8: e1003083
Darby MM, Serebreni L, Pan X, et al. (2012) The Saccharomyces cerevisiae Nrd1-Nab3 transcription termination pathway acts in opposition to Ras signaling and mediates response to nutrient depletion. Molecular and Cellular Biology. 32: 1762-75
Huang Z, Chen K, Xu T, et al. (2011) Sampangine inhibits heme biosynthesis in both yeast and human. Eukaryotic Cell. 10: 1536-44
Ben-Aroya S, Pan X, Boeke JD, et al. (2010) Making temperature-sensitive mutants. Methods in Enzymology. 470: 181-204
Pan X, Reissman S, Douglas NR, et al. (2010) Trivalent arsenic inhibits the functions of chaperonin complex. Genetics. 186: 725-34
Kim BJ, Li Y, Zhang J, et al. (2010) Genome-wide reinforcement of cohesin binding at pre-existing cohesin sites in response to ionizing radiation in human cells. The Journal of Biological Chemistry. 285: 22784-92
Matecic M, Smith DL, Pan X, et al. (2010) A microarray-based genetic screen for yeast chronological aging factors. Plos Genetics. 6: e1000921
Kim JH, Zhao Y, Pan X, et al. (2009) The unfolded protein response is necessary but not sufficient to compensate for defects in disulfide isomerization. The Journal of Biological Chemistry. 284: 10400-8
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