Li-Jiuan Shen, Ph.D.
Affiliations: | 2004 | University of Southern California, Los Angeles, CA, United States |
Area:
PharmacologyGoogle:
"Li-Jiuan Shen"Parents
Sign in to add mentor| Wei-Chiang Shen | grad student | 2004 | USC | |
| (Recombinant arginine deiminase (rADI) and arginine metabolism.) | ||||
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| Yeh TH, Chen YR, Chen SY, et al. (2015) Selective intracellular delivery of recombinant arginine deiminase (ADI) using pH-sensitive cell penetrating peptides to overcome ADI resistance in hypoxic breast cancer cells. Molecular Pharmaceutics |
| Wu FL, Yeh TH, Chen YL, et al. (2014) Intracellular delivery of recombinant arginine deiminase (rADI) by heparin-binding hemagglutinin adhesion peptide restores sensitivity in rADI-resistant cancer cells. Molecular Pharmaceutics. 11: 2777-86 |
| Shen LJ, Shen WC. (2006) Drug evaluation: ADI-PEG-20--a PEGylated arginine deiminase for arginine-auxotrophic cancers. Current Opinion in Molecular Therapeutics. 8: 240-8 |
| Shen LJ, Beloussow K, Shen WC. (2006) Modulation of arginine metabolic pathways as the potential anti-tumor mechanism of recombinant arginine deiminase. Cancer Letters. 231: 30-5 |
| Shen LJ, Beloussow K, Shen WC. (2005) Accessibility of endothelial and inducible nitric oxide synthase to the intracellular citrulline-arginine regeneration pathway. Biochemical Pharmacology. 69: 97-104 |
| Shen LJ, Lin WC, Beloussow K, et al. (2003) Recombinant arginine deiminase as a differential modulator of inducible (iNOS) and endothelial (eNOS) nitric oxide synthetase activity in cultured endothelial cells. Biochemical Pharmacology. 66: 1945-52 |
| Shen LJ, Lin WC, Beloussow K, et al. (2003) Resistance to the anti-proliferative activity of recombinant arginine deiminase in cell culture correlates with the endogenous enzyme, argininosuccinate synthetase. Cancer Letters. 191: 165-70 |