Mark Wewers

Affiliations: 
Biophysics Ohio State University, Columbus, Columbus, OH 
Area:
General Biophysics
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"Mark Wewers"
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Prather ER, Gavrilin MA, Wewers MD. (2022) The central inflammasome adaptor protein ASC activates the inflammasome after transition from a soluble to an insoluble state. The Journal of Biological Chemistry. 102024
Gavrilin MA, Prather ER, Vompe AD, et al. (2021) cAbl Kinase Regulates Inflammasome Activation and Pyroptosis via ASC Phosphorylation. Journal of Immunology (Baltimore, Md. : 1950)
Mitra S, Dolvin E, Krishnamurthy K, et al. (2018) Francisella induced microparticulate caspase-1/gasdermin-D activation is regulated by NLRP3 independent of Pyrin. Plos One. 13: e0209931
Hoang KV, Rajaram MVS, Curry HM, et al. (2018) Complement Receptor 3-Mediated Inhibition of Inflammasome Priming by Ras GTPase-Activating Protein During Phagocytosis by Human Mononuclear Phagocytes. Frontiers in Immunology. 9: 561
Ratner D, Orning MP, Proulx MK, et al. (2016) The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation. Plos Pathogens. 12: e1006035
Sundaram K, Rahman MA, Mitra S, et al. (2016) IκBζ Regulates Human Monocyte Pro-Inflammatory Responses Induced by Streptococcus pneumoniae. Plos One. 11: e0161931
Hoyt LR, Ather JL, Randall MJ, et al. (2016) Ethanol and Other Short-Chain Alcohols Inhibit NLRP3 Inflammasome Activation through Protein Tyrosine Phosphatase Stimulation. Journal of Immunology (Baltimore, Md. : 1950)
Martin BN, Wang C, Zhang CJ, et al. (2016) T cell-intrinsic ASC critically promotes TH17-mediated experimental autoimmune encephalomyelitis. Nature Immunology
Mitra S, Wewers MD, Sarkar A. (2015) Mononuclear Phagocyte-Derived Microparticulate Caspase-1 Induces Pulmonary Vascular Endothelial Cell Injury. Plos One. 10: e0145607
Shamaa OR, Mitra S, Gavrilin MA, et al. (2015) Monocyte Caspase-1 Is Released in a Stable, Active High Molecular Weight Complex Distinct from the Unstable Cell Lysate-Activated Caspase-1. Plos One. 10: e0142203
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