David G. Monroe, Ph.D.
Affiliations: | 2000 | University of Minnesota, Twin Cities, Minneapolis, MN |
Area:
Biochemistry, Molecular BiologyGoogle:
"David Monroe"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Michel M. Sanders | grad student | 2000 | UMN | |
| (Estrogen opposes apoptosis by repressing BMP-7 and initiator caspase gene transcription.) | ||||
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Publications
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| Doolittle ML, Eckhardt BA, Vos SJ, et al. (2023) Modest Effects of Osteoclast-Specific ERα Deletion after Skeletal Maturity. Jbmr Plus. 7: e10797 |
| Emch MJ, Wicik Z, Aspros KGM, et al. (2023) Estrogen-regulated miRs in bone enhance osteoblast differentiation and matrix mineralization. Molecular Therapy. Nucleic Acids. 33: 28-41 |
| Kaur J, Saul D, Doolittle ML, et al. (2023) -- Decreases with Age in Mice and Humans and Inhibits Osteoblast Senescence. Jbmr Plus. 7: e10745 |
| Farr JN, Saul D, Doolittle ML, et al. (2023) Local senolysis in aged mice only partially replicates the benefits of systemic senolysis. The Journal of Clinical Investigation |
| Saul D, Kosinsky RL, Atkinson EJ, et al. (2022) A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues. Nature Communications. 13: 4827 |
| Doolittle ML, Saul D, Kaur J, et al. (2022) Skeletal Effects of Inducible ERα Deletion in Osteocytes in Adult Mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research |
| Doolittle ML, Monroe DG, Farr JN, et al. (2021) The role of senolytics in osteoporosis and other skeletal pathologies. Mechanisms of Ageing and Development. 199: 111565 |
| Jayaraman S, Hou X, Kuffel MJ, et al. (2020) Antitumor activity of Z-endoxifen in aromatase inhibitor-sensitive and aromatase inhibitor-resistant estrogen receptor-positive breast cancer. Breast Cancer Research : Bcr. 22: 51 |
| Eckhardt BA, Rowsey JL, Thicke BS, et al. (2020) Accelerated osteocyte senescence and skeletal fragility in mice with type 2 diabetes. Jci Insight |
| Chandra A, Lagnado AB, Farr JN, et al. (2020) Targeted reduction of senescent cell burden alleviates focal radiotherapy-related bone loss. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research |