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Eric A. Sobie

Affiliations: 
Biophysics, Structural Biology, and Biomathematics Mount Sinai School of Medicine, New York, NY 
Area:
Physiology Biology, Pathology, Applied Mathematics
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"Eric Sobie"
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Parents

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Leslie Tung grad student Johns Hopkins

Children

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Amrita Sarkar grad student 2011 Mount Sinai

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Publications

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Gando I, Campana C, Tan RB, et al. (2020) A distinct molecular mechanism by which phenytoin rescues a novel long QT 3 variant. Journal of Molecular and Cellular Cardiology
Gong JQX, Susilo ME, Sher A, et al. (2020) Quantitative analysis of variability in an integrated model of human ventricular electrophysiology and β-adrenergic signaling. Journal of Molecular and Cellular Cardiology
Li Z, Mirams GR, Yoshinaga T, et al. (2019) General Principles for the Validation of Proarrhythmia Risk Prediction Models: An Extension of the CiPA In Silico Strategy. Clinical Pharmacology and Therapeutics
Jones DC, Sobie EA. (2019) Mechanistic Differences between Ca2+Sparks and Ca2Puffs Revealed Through Simulations of Heterogeneous Populations Biophysical Journal. 116: 401a
Varshneya M, Devenyi RA, Sobie EA. (2018) Slow Delayed Rectifier Current Protects Ventricular Myocytes From Arrhythmic Dynamics Across Multiple Species. Circulation. Arrhythmia and Electrophysiology. 11: e006558
Mora MT, Ferrero JM, Gomez JF, et al. (2018) Ca Cycling Impairment in Heart Failure Is Exacerbated by Fibrosis: Insights Gained From Mechanistic Simulations. Frontiers in Physiology. 9: 1194
Mayourian J, Sobie EA, Costa KD. (2018) An Introduction to Computational Modeling of Cardiac Electrophysiology and Arrhythmogenicity. Methods in Molecular Biology (Clifton, N.J.). 1816: 17-35
Jones DC, Gong JQX, Sobie EA. (2018) A privileged role for neuronal Na channels in regulating ventricular [Ca] and arrhythmias. The Journal of General Physiology
Campana C, Gando I, Bianca Tan R, et al. (2018) Population-Based Mathematical Modeling to Deduce Disease-Causing Cardiac Na+ Channel Gating Defects Biophysical Journal. 114: 634a-635a
Shim JV, Chun B, van Hasselt JGC, et al. (2017) Mechanistic Systems Modeling to Improve Understanding and Prediction of Cardiotoxicity Caused by Targeted Cancer Therapeutics. Frontiers in Physiology. 8: 651
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